SCHEMBL1426317

SCHEMBL1426317

CC1C(=O)NC(=O)N(C2CCCCC2)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
GAA P10253 2/20 0.49
POLB P06746 1/20 0.49
OPRM1 P35372 1/20 0.42
OPRK1 P41145 1/20 0.42
OPRL1 P41146 1/20 0.42
ALDH1A1 P00352 6/20 0.42
CYP2C9 P11712 5/20 0.42
CYP2C19 P33261 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
CYP3A4 P08684 3/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.40
ALOX15 P16050 1/20 0.40
HTT P42858 1/20 0.40
CREBBP Q92793 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268831 0.82 LMNA (0.54) LMNAGAAPOLBOPRM1OPRK1
SCHEMBL94928 0.77 ALDH1A1 (0.53) LMNAGAAPOLBOPRM1OPRK1
SCHEMBL17358748 0.76 MAPT (0.50) LMNAGAAPOLBALDH1A1CYP2C9
SCHEMBL15744622 0.76 LMNA (0.53) LMNAGAAPOLBOPRM1OPRK1
Propane SCHEMBL9334285 0.76 ALDH1A1 (0.51) LMNAGAAPOLBOPRM1OPRK1
SCHEMBL11388333 0.76 BBOX1 (0.42) LMNAGAAPOLBALDH1A1CYP2C9
SCHEMBL1426482 0.76 ALDH1A1 (0.51) LMNAGAAPOLBOPRM1OPRK1
SCHEMBL17472455 0.75 ALDH1A1 (0.49) LMNAGAAPOLBOPRM1OPRK1
Hydrochloric Acid SCHEMBL9420413 0.75 ALDH1A1 (0.50) LMNAGAAPOLBOPRM1OPRK1
SCHEMBL15974259 0.73 LMNA (0.71) LMNAGAAPOLBOPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE KURARAY NORITAKE DENTAL INC. (JP) 2025-06-26 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-3542775-B1 COMPOSITION WITH EXCELLENT STORAGE STABILITY USING HIGHLY BASIC FILLER SHOFU INC (JP) 2025-04-02 EP disclosed
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER SHOFU INC (JP) 2025-02-27 US disclosed
US-20250057733-A1 CURABLE DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
US-20250057732-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
CN-101595138-A Polymerizable monomer-containing composition KURARAY MEDICAL INC (JP) 2009-12-02 CN disclosed
CN-101589070-A Composition and dental material KURARAY MEDICAL INC (JP) 2009-11-25 CN disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
CN-101547930-A Novel compound, composition containing same, and method for producing polymerizable amide KURARAY MEDICAL INC (JP) 2009-09-30 CN disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed
JP-2006124412-A RADICAL POLYMERIZATION INITIATOR AND DENTAL CURABLE COMPOSITION TOKUYAMA CORP 2006-05-18 JP disclosed
JP-2000007518-A HARDENABLE DENTAL KIT TOKUYAMA CORP 2000-01-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 LMNA 35/4885GAA 1077/4885POLB 1042/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A LMNA 133/4885GAA 1661/4885POLB 402/4885
US-20250064686-A1 DENTAL CURABLE COMPOSITION CONTAINING ULTRAVIOLET ABSORBER ERCC1, DSC1, CRYAA LMNA 794/4885GAA 2946/4885POLB 839/4885
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE ACR, CAD, ALG3 LMNA 2804/4885GAA 3626/4885POLB 3166/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL LMNA 2975/4885GAA 3536/4885POLB 4114/4885
US-20250057732-A1 DENTAL CURABLE COMPOSITION CAD, MMAB, DNMT3L LMNA 2132/4885GAA 1823/4885POLB 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.