SCHEMBL14450855

SCHEMBL14450855

C=C1CCC(=O)N1OC(=O)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258692 0.87 MGLL (0.36) GLA
SCHEMBL20624817 0.86
SCHEMBL16938480 0.83 ALDH1A1 (0.33)
SCHEMBL21232206 0.83
SCHEMBL17861182 0.83
SCHEMBL18916122 0.82 TSHR (0.31)
SCHEMBL13286374 0.82 MGLL (0.32)
SCHEMBL8402012 0.81 MGLL (0.32)
SCHEMBL15371562 0.80 KMT2A (0.32)
SCHEMBL12482068 0.79 GLA (0.36) GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11857638-B2 Quinone-containing conjugates PROMEGA CORPORATION (US) 2024-01-02 US disclosed
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2023-11-28 US disclosed
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 US disclosed
US-20230272002-A1 PHOTOREDOX PROTEIN MODIFICATION THE ROSALIND FRANKLIN INSTITUTE (GB) 2023-08-31 US disclosed
US-11697736-B2 Silicon containing detectable compounds Singular Genomics Systems, Inc. (US) 2023-07-11 US disclosed
WO-2023129518-A1 TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES REGENERON PHARMACEUTICALS, INC. (US) 2023-07-06 WO disclosed
US-20230160001-A1 NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-05-25 US disclosed
US-11649452-B2 High density sequencing and multiplexed priming Singular Genomics Systems, Inc. (US) 2023-05-16 US disclosed
US-20210386680-A1 SELECTIVELY CLEAVABLE THERAPEUTIC NANOPARTICLES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2021-12-16 US disclosed
US-20210275718-A1 Crosslinked Gels Comprising Polyalkyleneimines, And Their Uses As Medical Devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2021-09-09 US disclosed
US-10688216-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2020-06-23 US disclosed
US-20190001018-A1 CROSSLINKED GELS COMPRISING POLYALKYLENEIMINES, AND THEIR USES AS MEDICAL DEVICES HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2019-01-03 US disclosed
US-9878066-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2018-01-30 US disclosed
US-20170362266-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions THE GENERAL HOSPITAL CORPORATION 2017-12-21 US disclosed
US-20170199201-A2 SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-07-13 US disclosed
US-9417248-B2 Surrogates of post-translationally modified proteins and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-08-16 US disclosed
US-9365721-B2 Polycyclo dyes and use thereof VISEN MEDICAL, INC. (US) 2016-06-14 US disclosed
US-20150175998-A1 Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs NORTHWESTERN UNIVERSITY 2015-06-25 US disclosed
US-20140024056-A1 SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2014-01-23 US disclosed
US-7238339-B2 Bifunctional chelating compounds containing hydroxamic acid residues DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) 2007-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10688216-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, LIG3, PLOD2 GLA 2117/4885
US-11697736-B2 Silicon containing detectable compounds AS3MT, SCLY, NASP GLA 425/4885
US-20210275718-A1 Crosslinked Gels Comprising Polyalkyleneimines, And Their Uses As Medical Devices PLOD3, LIG3, PLOD2 GLA 2117/4885
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS AS3MT, SCLY, NASP GLA 425/4885
US-20230272002-A1 PHOTOREDOX PROTEIN MODIFICATION PPOX, CACYBP, BRI3BP GLA 3857/4885
US-20210386680-A1 SELECTIVELY CLEAVABLE THERAPEUTIC NANOPARTICLES MMP10, MMP1, MMP3 GLA 324/4885
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, LIG3, PLOD2 GLA 2117/4885
US-20140024056-A1 SURROGATES OF POST-TRANSLATIONALLY MODIFIED PROTEINS AND USES THEREOF CD59, SIGLEC9, CD209 GLA 878/4885
US-20170362266-A1 Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions GALNT14, NEU4, CSGALNACT1 GLA 27/4885
US-11857638-B2 Quinone-containing conjugates NQO1, NQO2, SQOR GLA 1955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.