Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530270 | 0.76 | OPRD1 (0.59) | SIGMAR1POLBLMNA | |
| SCHEMBL11843293 | 0.72 | SIGMAR1 (0.44) | SIGMAR1HTR2CSLC6A2HTR2BSLC6A3 | |
| SCHEMBL18169342 | 0.71 | ALDH1A1 (0.47) | SIGMAR1ALOX15ALDH1A1TDP1MEN1 | |
| SCHEMBL10515637 | 0.69 | HTR2A (0.49) | ALOX15KMT2AHTR2CHTR2BMAPKAPK2 | |
| SCHEMBL14530329 | 0.68 | SIGMAR1 (0.63) | SIGMAR1OPRM1ADRA2AOPRK1 | |
| SCHEMBL11684159 | 0.68 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2AHTR2CSLC6A2 | |
| SCHEMBL14529832 | 0.67 | SIGMAR1 (0.72) | SIGMAR1ADRA2A | |
| SCHEMBL11739762 | 0.67 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1HTR2COPRM1ADRB2 | |
| SCHEMBL24650763 | 0.67 | ALDH1A1 (0.43) | SIGMAR1ALOX15ALDH1A1TDP1MEN1 | |
| SCHEMBL11737034 | 0.67 | RAB9A (0.35) | SIGMAR1ALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |