Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12455448 | 0.87 | KDM4E (0.44) | GAAKDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL22370027 | 0.87 | KDM4E (0.44) | GAAKDM4EALDH1A1HPGDALOX12 | |
| SCHEMBL22370015 | 0.82 | RXFP1 (0.35) | GAA | |
| SCHEMBL24469180 | 0.80 | KMT2A (0.37) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29141518 | 0.78 | — | — | |
| SCHEMBL24429757 | 0.73 | LMNA (0.36) | MEN1KMT2A | |
| SCHEMBL12570336 | 0.72 | GPR3 (0.40) | GAAKDM4EALDH1A1GPR3MEN1 | |
| SCHEMBL16726437 | 0.72 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL16726511 | 0.72 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL22370040 | 0.71 | ADORA3 (0.35) | GAAKDM4EALDH1A1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758416-B1 | NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9545624-B2 | Nickel containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-9480977-B2 | Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-9221041-B2 | Iridium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-09-04 | — | — | US | disclosed |
| US-20140206869-A1 | Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-24 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| WO-2013043912-A2 | IRON CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043787-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206869-A1 | Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | ILK, ALG8, HIRA | GAA 1124/4885KDM4E 4326/4885ALDH1A1 1484/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | GAA 901/4885KDM4E 4572/4885ALDH1A1 2299/4885 |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | TFRC, FTH1, HAMP | GAA 1280/4885KDM4E 3975/4885ALDH1A1 1738/4885 |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ITGA1, TMT1A, ITGA2 | GAA 486/4885KDM4E 4263/4885ALDH1A1 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.