SCHEMBL1486898

SCHEMBL1486898

O=C([O-])c1cccc([N+](=O)[O-])c1.[Na+]

nearest known ligand 0.72

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.60
CA2 known ✓ P00918 2/20 0.60
CES2 O00748 1/20 0.72
CES1 P23141 1/20 0.72
TP53 P04637 1/20 0.70
ALDH1A1 P00352 5/20 0.68
TSHR P16473 4/20 0.68
KMT2A Q03164 5/20 0.60
MEN1 O00255 4/20 0.60
LMNA P02545 1/20 0.59
PRSS1 P07477 1/20 0.59
PRSS2 P07478 1/20 0.59
PRSS3 P35030 1/20 0.59
RXFP1 Q9HBX9 1/20 0.55
ALOX15 P16050 1/20 0.55
MAPT P10636 4/20 0.54
POLB P06746 2/20 0.54
BLM P54132 1/20 0.54
HTT P42858 2/20 0.54
RAB9A P51151 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9687725 0.98 CES2 (0.70) CES2CES1TP53ALDH1A1TSHR
Potassium Ion SCHEMBL11534869 0.96 CES2 (0.72) CES2CES1TP53ALDH1A1TSHR
Silver SCHEMBL11320109 0.96 CES2 (0.72) CES2CES1TP53ALDH1A1TSHR
Zinc Ion SCHEMBL8816395 0.96 CES2 (0.72) CES2CES1TP53ALDH1A1TSHR
Lithium Ion SCHEMBL29084353 0.96 CES2 (0.72) CES2CES1TP53ALDH1A1TSHR
SCHEMBL10415666 0.85 TP53 (0.96) CES2CES1TP53ALDH1A1TSHR
SCHEMBL2156825 0.84 CES1 (1.00) CES2CES1TP53ALDH1A1TSHR
SCHEMBL181572 0.84 CES2 (0.78) CES2CES1TP53ALDH1A1TSHR
SCHEMBL31374765 0.84 CES1 (1.00) CES2CES1TP53ALDH1A1TSHR
SCHEMBL8962468 0.82 CES2 (0.75) CES2CES1TP53ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119530899-A Sulfite electroforming gold liquid and preparation method thereof 北京金百镀科技有限公司 2025-02-28 CN claimed
CN-119220184-A Alkali polishing additive for rapid polishing of monocrystalline silicon and application method thereof 嘉兴市小辰光伏科技有限公司 2024-12-31 CN claimed
CN-115254395-B Method for separating arsenic and sulfur in zinc tailings 中国矿业大学(北京) 2024-09-27 CN claimed
US-11932948-B2 Electroless nickel etch chemistry, method of etching and pretreatment HUTCHINSON TECHNOLOGY INCORPORATED (US) 2024-03-19 US claimed
CN-117696263-A Sulfur arsenic flotation separation inhibitor for pyrite, and preparation method and application thereof 沈阳有色金属研究院有限公司 2024-03-15 CN claimed
CN-114703520-B Cyanide-free electroplating gold liquid, preparation method and application thereof, gold-plated part and preparation method thereof 深圳市联合蓝海黄金材料科技股份有限公司 2023-03-31 CN claimed
CN-115254395-A Method for separating arsenic and sulfur in zinc tailings 中国矿业大学(北京) 2022-11-01 CN claimed
CN-115094488-A Method for manufacturing thin-sheet precious metal product and product 深圳市崇宁实业有限公司 2022-09-23 CN claimed
CN-114703520-A Cyanide-free electroplating gold liquid, preparation method and application thereof, gold-plated part and preparation method thereof 深圳市联合蓝海黄金材料科技股份有限公司 2022-07-05 CN claimed
US-20220127729-A1 Electroless Nickel Etch Chemistry, Method Of Etching And Pretreatment HUTCHINSON TECHNOLOGY INCORPORATED 2022-04-28 US claimed
US-7914633-B1 White propellant compositions HODGDON POWDER COMPANY, INC. (US) 2011-03-29 US claimed
US-7344610-B2 Sulfur-free propellant compositions HODGDON POWDER COMPANY, INC. (US) 2008-03-18 US claimed
US-20040144457-A1 Sulfur-free propellant compositions HODGDON POWDER COMPANY, INC. 2004-07-29 US claimed
US-5817624-A Permeation enhancer compositions for increased absorption of therapeutic proteins through the colonic membrane ALZA CORPORATION (US) 1998-10-06 US claimed
US-5338343-A Using a water soluble organic thiol gold(I) complex, an alkali metal cyanide, an alkali metal hydroxide, a borohydride reducing agent; deposits gold faster than conventional baths TECHNIC INCORPORATED (US) 1994-08-16 US claimed
US-5212261-A LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS HENKEL RESEARCH CORPORATION (US) 1993-05-18 US claimed
WO-1992011307-A1 LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS HENKEL RESEARCH CORPORATION (US) 1992-07-09 WO claimed
EP-0203423-B1 PROCESS FOR FORMING A METALLURGICAL SYSTEM COMPRISING A BOTTOM LAYER OF NICKEL AND A TOP LAYER OF GOLD International Business Machines Corporation (US) 1989-09-27 EP claimed
EP-0203423-A1 Process for forming a metallurgical system comprising a bottom layer of nickel and a top layer of gold International Business Machines Corporation (US) 1986-12-03 EP claimed
US-3958984-A ALKALI CYANIDE, NITRO AROMATIC FOUNTAIN LAURENCE R 1976-05-25 US claimed