SCHEMBL15413402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1270667	0.97	ESR1 (0.39)	ESR1ESR2ALDH1A1TRPA1MAPK1
	SCHEMBL852172	0.77	MAPT (0.44)	ESR1ESR2ALDH1A1TRPA1MAPK1
	SCHEMBL10950698	0.76	PTGS1 (0.38)	—
	SCHEMBL1270651	0.76	ESR1 (0.42)	ESR1ESR2ALDH1A1MAPTLMNA
	SCHEMBL9225762	0.76	ESR1 (0.42)	ESR1ESR2ALDH1A1MAPTLMNA
	SCHEMBL10940146	0.75	LMNA (0.40)	ALDH1A1GSK3BLMNAKMT2A
	SCHEMBL10444591	0.75	ESR1 (0.38)	ESR1ESR2ALDH1A1TRPA1MAPK1
	SCHEMBL3238058	0.75	ESR1 (0.34)	ESR1ESR2MAPT
	SCHEMBL12191013	0.74	ESR1 (0.41)	ESR1ESR2ALDH1A1MAPTLMNA
	SCHEMBL9358733	0.73	ACHE (0.36)	LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.