Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661047 | 1.00 | GPR84 (0.38) | GPR84CA2RECQLNFKB1CA1 | |
| SCHEMBL5245402 | 0.87 | GPR84 (0.43) | GPR84RECQLTP53TSHRMEN1 | |
| SCHEMBL5245593 | 0.87 | GPR84 (0.43) | GPR84RECQLTP53TSHRMEN1 | |
| SCHEMBL5411291 | 0.87 | RECQL (0.45) | GPR84RECQLTP53TSHRABCB1 | |
| SCHEMBL5247782 | 0.87 | GPR84 (0.43) | GPR84RECQLTP53TSHRMEN1 | |
| SCHEMBL5244490 | 0.87 | GPR84 (0.43) | GPR84RECQLTP53TSHRMEN1 | |
| SCHEMBL10334312 | 0.84 | SLC25A20 (0.38) | GPR84CA2RECQLNFKB1CA1 | |
| SCHEMBL478459 | 0.84 | GPR84 (0.42) | GPR84CA2RECQLNFKB1CA1 | |
| SCHEMBL8376547 | 0.84 | GPR84 (0.42) | GPR84CA2RECQLNFKB1CA1 | |
| SCHEMBL7762175 | 0.83 | CA2 (0.44) | GPR84CA2RECQLNFKB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111629820-B | Hardenable multipart acrylic composition | 三菱化学英国有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-11548966-B2 | Hardenable multi-part acrylic composition | LUCITE INTERNATIONAL SPECIALTY POLYMERS AND RESINS LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
| US-11370865-B2 | Hardenable multi-part acrylic composition | Mitsubishi Chemical UK Limited (GB) | 2022-06-28 | — | — | US | disclosed |
| CN-114651045-A | Transparent thermoplastic resin and method for producing same | 株式会社LG化学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114641530-A | Transparent thermoplastic resin and method for producing same | 株式会社LG化学 | 2022-06-17 | — | — | CN | disclosed |
| CN-110168001-B | Environmentally curable coating composition for cables and cable fittings | 通用线缆技术公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114514282-A | Thermoplastic resin and method for producing same | 株式会社LG化学 | 2022-05-17 | — | — | CN | disclosed |
| CN-114502646-A | Thermoplastic resin and method for producing same | 株式会社LG化学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478973-A | Aqueous polyurethane resin and preparation method thereof | 南亚塑胶工业股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114342124-A | Binder composition for secondary battery | 广东省皓智科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20100029842-A1 | Copolymers Made Of Alkylene Oxides And Glycidyl Ethers And Use Thereof As Polymerizable Emulsifiers | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7605224-B2 | Reacting alkylene oxide and glycidy ether to produce OH- or acid-terminated copolymer | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2009-10-20 | — | — | US | disclosed |
| US-20080227917-A1 | Copolymers made of alkylene oxides and glycidyl ethers and use thereof as polymerizable emulsifiers | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH | 2008-09-18 | — | — | US | disclosed |
| US-7388068-B2 | Copolymers made of alkylene oxides and glycidyl ethers and use thereof as polymerizable emulsifiers | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-06-17 | — | — | US | disclosed |
| US-20050261457-A1 | Copolymers made of alkylene oxides and glycidyl ethers and use thereof as polymerisable emulsifiers | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| EP-0820478-B1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEM CO (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5869590-A | SOLVENT, PRINT AND BLOCK RESISTANCE | EASTMAN CHEMICAL COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0820478-A1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEMICAL COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032429-A1 | WATERBORNE POLYMERS HAVING PENDANT ALLYL GROUPS | EASTMAN CHEMICAL COMPANY (US) | 1996-10-17 | — | — | WO | disclosed |
| US-5539073-A | FREE RADICAL CROSSLINKING AFTER FILM FORMATION | EASTMAN CHEMICAL COMPANY (US) | 1996-07-23 | — | — | US | disclosed |