Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14002603 | 0.80 | — | — | |
| SCHEMBL5135507 | 0.75 | MMP2 (0.35) | CYP1A1CYP1A2CYP1B1MMP2 | |
| SCHEMBL16993776 | 0.70 | — | — | |
| SCHEMBL515092 | 0.70 | — | — | |
| SCHEMBL1145575 | 0.70 | — | — | |
| SCHEMBL23829792 | 0.65 | ACLY (0.34) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL24843796 | 0.65 | — | — | |
| SCHEMBL21965726 | 0.65 | CYP1A1 (0.33) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7770920 | 0.65 | — | — | |
| SCHEMBL14876788 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751364-A | Dimethoxy quinazoline compound and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | claimed |
| US-20210403449-A1 | BIPHENYL DIARYL PYRIMIDINE DERIVATIVE WITH AROMATIC HETEROCYCLIC STRUCTURE | FUDAN UNIVERSITY (CN) | 2021-12-30 | — | — | US | claimed |
| US-12522813-B2 | Mannanase for formulations having pH 5-12 | BASF SE (DE) | 2026-01-13 | — | — | US | disclosed |
| US-20250243181-A2 | NOVEL INDAZOLE DERIVATIVE AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2025-07-31 | — | — | US | disclosed |
| CN-120118071-A | Quinazoline compound and application thereof | 北京化工大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119751364-A | Dimethoxy quinazoline compound and application thereof | 中日友好医院(中日友好临床医学研究所) | 2025-04-04 | — | — | CN | disclosed |
| US-20240287060-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-08-29 | — | — | US | disclosed |
| US-20240132808-A1 | Storage-Stable Hydrolase Containing Liquids | BASF SE (DE) | 2024-04-25 | — | — | US | disclosed |
| US-11912685-B2 | Biphenyl diaryl pyrimidine derivative with aromatic heterocyclic structure | FUDAN UNIVERSITY (CN) | 2024-02-27 | — | — | US | disclosed |
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | disclosed |
| US-11866436-B2 | Benzo[c][2,6]naphthyridine derivatives, compositions and therapeutic uses thereof | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-01-09 | — | — | US | disclosed |
| US-20040106559-A1 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-06-03 | — | — | US | disclosed |
| US-20040087626-A1 | Substituted benz-azoles and methods of their use as inhibitors of Raf kinase | NOVARTIS AG (CH) | 2004-05-06 | — | — | US | disclosed |
| US-20040063674-A1 | Tetracycline compounds having target therapeutic activities | PARATEK PHARMACEUTICALS, INC. | 2004-04-01 | — | — | US | disclosed |
| EP-1381372-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS AS SYNERGISTIC ANTIFUNGAL AGENTS | Paratek Pharmaceuticals, Inc. (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2003099274-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003082272-A1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS | CHIRON CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| WO-2003079984-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2003-10-02 | — | — | WO | disclosed |
| US-20030166585-A1 | Substituted tetracycline compounds as synergistic antifungal agents | PARATEK PHARMACEUTICALS, INC. | 2003-09-04 | — | — | US | disclosed |
| WO-2002072031-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS AS SYNERGISTIC ANTIFUNGAL AGENTS | PARATEK PHARMACEUTICALS, INC. (US) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166585-A1 | Substituted tetracycline compounds as synergistic antifungal agents | TUBB6, ETF1, TUBB2A | CYP1A1 2886/4885CYP1A2 1917/4885CYP1B1 3290/4885 |
| US-20040087626-A1 | Substituted benz-azoles and methods of their use as inhibitors of Raf kinase | BRAF, RAF1, ARAF | CYP1A1 1128/4885CYP1A2 1518/4885CYP1B1 691/4885 |
| US-11912685-B2 | Biphenyl diaryl pyrimidine derivative with aromatic heterocyclic structure | DPYD, TYMP, DHODH | CYP1A1 262/4885CYP1A2 212/4885CYP1B1 174/4885 |
| US-20250243181-A2 | NOVEL INDAZOLE DERIVATIVE AND USE THEREOF | TRIB2, YAP1, IDO2 | CYP1A1 1547/4885CYP1A2 273/4885CYP1B1 1009/4885 |
| US-20040063674-A1 | Tetracycline compounds having target therapeutic activities | TBCA, TUBB6, TUBB | CYP1A1 3389/4885CYP1A2 2912/4885CYP1B1 3921/4885 |
| US-11866436-B2 | Benzo[c][2,6]naphthyridine derivatives, compositions and therapeutic uses thereof | ABCB11, CEL, NDC1 | CYP1A1 320/4885CYP1A2 115/4885CYP1B1 210/4885 |
| US-20240287060-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CSNK1A1, CSNK1D, CSNK2A1 | CYP1A1 1786/4885CYP1A2 2017/4885CYP1B1 1817/4885 |
| US-20040106559-A1 | Hepatitis C virus inhibitors | HAVCR2, HCCS, RNASE1 | CYP1A1 121/4885CYP1A2 138/4885CYP1B1 33/4885 |
| US-20210403449-A1 | BIPHENYL DIARYL PYRIMIDINE DERIVATIVE WITH AROMATIC HETEROCYCLIC STRUCTURE | DPYD, TYMP, DHODH | CYP1A1 262/4885CYP1A2 212/4885CYP1B1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.