Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103505 | 0.75 | APOL1 (0.33) | — | |
| SCHEMBL859494 | 0.74 | APOL1 (0.33) | — | |
| SCHEMBL21583074 | 0.73 | NAAA (0.38) | — | |
| SCHEMBL21185836 | 0.73 | LMNA (0.39) | — | |
| SCHEMBL12723119 | 0.72 | SSTR4 (0.41) | — | |
| SCHEMBL13163338 | 0.72 | SSTR4 (0.41) | — | |
| SCHEMBL7766475 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL6390746 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL26939020 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL18211227 | 0.70 | POLB (0.42) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042550-B2 | Leave-on hair treatment compositions | L'OREAL (FR) | 2024-07-23 | — | — | US | claimed |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-18 | — | — | US | claimed |
| WO-2024073637-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-04 | — | — | WO | claimed |
| EP-1965757-B1 | COSMETIC USE OF A HYDROXYALKYLUREA AS AN AGENT FOR TREATING DESQUAMATIVE CONDITIONS OF THE SCALP; COSMETIC TREATMENT COMPOSITIONS AND PROCESSES | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| EP-1743623-B1 | Use of urea compounds for promoting desquamation | ORÉAL L (FR) | 2016-06-29 | — | — | EP | claimed |
| EP-1674072-B1 | Use of urea compounds to combat indications of skin ageing | ORÉAL L (FR) | 2014-06-04 | — | — | EP | claimed |
| US-8173144-B2 | Administration of urea compounds for combating signs of cutaneous aging | L'OREAL (FR) | 2012-05-08 | — | — | US | claimed |
| US-7999008-B2 | Urea compounds that promote desquamation | L'OREAL (FR) | 2011-08-16 | — | — | US | claimed |
| EP-1661550-B1 | Cosmetic and/or dermatological composition comprising urea compound | OREAL (FR) | 2011-04-27 | — | — | EP | claimed |
| EP-1824447-B1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-20060193813-A1 | Nanoemulsion containing a hydroxylated urea compound | L'OREAL (FR) | 2006-08-31 | — | — | US | claimed |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| WO-2006056491-A1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | L'ORÉAL (FR) | 2006-06-01 | — | — | WO | claimed |
| US-20060111490-A1 | Composition comprising a urea compound | L'OREAL (FR) | 2006-05-25 | — | — | US | claimed |
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | CUTA, S100A11, KRT18 | POLB 751/4885 |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | HCN3, KRT18, H1-0 | POLB 373/4885 |
| US-12042550-B2 | Leave-on hair treatment compositions | ALG3, DEGS1, DSG1 | POLB 932/4885 |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | KRT18, CUTA, H1-0 | POLB 520/4885 |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | H1-0, KRT18, CCNE1 | POLB 472/4885 |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | ALG3, DEGS1, DSG1 | POLB 932/4885 |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | SLC14A1, CTRL, URB2 | POLB 564/4885 |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | CUTA, TYR, ADH7 | POLB 564/4885 |
| US-20060193813-A1 | Nanoemulsion containing a hydroxylated urea compound | LIPA, AUP1, NONO | POLB 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.