SCHEMBL16013191

SCHEMBL16013191

[N-]=[N+]=NCCCOC(=O)NCCCCC(NC(=O)OCCCN=[N+]=N)C(=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 7/20 0.32
▸ TGM2 P21980 1/20 0.31
▸ FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17411108 0.85 ACHE (0.37) ACHETGM2FOLH1
SCHEMBL16013190 0.84 TGM2 (0.43) TGM2FOLH1
SCHEMBL16013473 0.81 ACHE (0.40) ACHETGM2
SCHEMBL17411215 0.81 ACHE (0.40) ACHETGM2
SCHEMBL27446533 0.78 ACHE (0.43) ACHETGM2
SCHEMBL16013082 0.77 ACHE (0.51) ACHE
SCHEMBL18532395 0.76 ACHE (0.39) ACHE
SCHEMBL17411140 0.74 ACHE (0.34) ACHETGM2
SCHEMBL16446646 0.73 DDAH1 (0.42) ACHE
SCHEMBL30030056 0.70 TDP1 (0.47) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964224-B1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2024-07-03 — — EP disclosed
US-10758626-B2 Polymer conjugate comprising a bioactive agent POLYACTIVA PTY LTD (AU) 2020-09-01 — — US disclosed
US-10111886-B2 Polymer conjugate for delivery of a bioactive agent POLYACTIVA PTY LTD (AU) 2018-10-30 — — US disclosed
US-10113033-B2 Polymer conjugate for delivery of a bioactive agent POLYACTIVA PTY LTD (AU) 2018-10-30 — — US disclosed
US-20180303948-A1 POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2018-10-25 — — US disclosed
US-20170216308-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2017-08-03 — — US disclosed
US-20170182173-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2017-06-29 — — US disclosed
US-9572892-B2 Polymer conjugate for delivery of a bioactive agent POLYACTIVA PTY LTD (AU) 2017-02-21 — — US disclosed
EP-2964224-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT Polyactiva Pty Ltd (AU) 2016-01-13 — — EP disclosed
US-20160000929-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2016-01-07 — — US disclosed
WO-2014134689-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2014-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10113033-B2 Polymer conjugate for delivery of a bioactive agent PTGIS, PTGIR, PGF ACHE 1848/4885TGM2 754/4885FOLH1 962/4885
US-10758626-B2 Polymer conjugate comprising a bioactive agent MSN, PAM, PARG ACHE 393/4885TGM2 3656/4885FOLH1 3363/4885
US-10111886-B2 Polymer conjugate for delivery of a bioactive agent PTGIS, PTGIR, PGF ACHE 797/4885TGM2 1012/4885FOLH1 1409/4885
US-20180303948-A1 POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT MSN, PAM, PARG ACHE 393/4885TGM2 3656/4885FOLH1 3363/4885
US-20160000929-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT PTGIS, PTGIR, PGF ACHE 939/4885TGM2 987/4885FOLH1 1105/4885
US-20170216308-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT PTGIS, PTGIR, PGF ACHE 797/4885TGM2 1012/4885FOLH1 1409/4885
US-20170182173-A1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT PTGIS, PTGIR, PGF ACHE 1848/4885TGM2 754/4885FOLH1 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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