Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608928 | 0.82 | CA1 (0.36) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL3695599 | 0.81 | KIF11 (0.33) | — | |
| SCHEMBL15404639 | 0.80 | PGR (0.51) | PGRARNPSR1TSHRRAB9A | |
| SCHEMBL1066922 | 0.80 | GPR3 (0.40) | EPHX2MAPTRAB9ACYP1A2KDM4E | |
| SCHEMBL3284666 | 0.79 | PDK2 (0.37) | MAPTALDH1A1CYP1A2PDK2KDM4E | |
| SCHEMBL6224540 | 0.79 | NQO1 (0.40) | ARTSHRCA1CA7CA9 | |
| SCHEMBL7230309 | 0.78 | ALDH1A1 (0.35) | NPSR1CA1CA2CA7CA9 | |
| SCHEMBL1636880 | 0.77 | PDK2 (0.40) | NPSR1CA1CA2CA7CA9 | |
| SCHEMBL5583736 | 0.77 | AR (0.51) | ARL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28008866 | 0.77 | LTA4H (0.46) | ARCA2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | claimed |
| WO-2024073282-A2 | HETEROCYCLES AS MODULATORS OF NSD ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-04-04 | — | — | WO | claimed |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-31 | — | — | US | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. | 2020-09-15 | — | — | US | claimed |
| US-10272072-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2019-04-30 | — | — | US | claimed |
| US-20170368039-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA TM, LLC (US) | 2017-12-28 | — | — | US | claimed |
| EP-2318006-B1 | NOVEL PYRROLE INHIBITORS OF S-NITROSOGLUTATHIONE REDUCTASE AS THERAPEUTIC AGENTS | NIVALIS THERAPEUTICS INC (US) | 2016-10-12 | — | — | EP | claimed |
| US-9138427-B2 | Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents | NIVALIS THERAPEUTICS, INC. (US) | 2015-09-22 | — | — | US | claimed |
| EP-1200373-A1 | METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS | Clariant GmbH (DE) | 2002-05-02 | — | — | EP | claimed |
| US-6353136-B1 | SUBSTITUTED ANILINES; ONLY VERY SMALL AMOUNTS OF CATALYST ARE NECESSARY SO COSTS ARE LESS; AMINATING AN AROMATIC HALIDE WITH AN AMINE | CLARIANT GMBH (DE) | 2002-03-05 | — | — | US | claimed |
| EP-1083163-A2 | Catalytic method for the preparation of aromatic amines using a palladaphosphacyclobutane compound as catalyst | Clariant GmbH (DE) | 2001-03-14 | — | — | EP | claimed |
| US-6194627-B1 | REACTING HALOAROMATIC COMPOUND WITH OLEFIN IN PRESENCE OF PALLADIUM COMPOUND AS CATALYST | AVENTIS RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) | 2001-02-27 | — | — | US | claimed |
| WO-2001004076-A1 | METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS | CLARIANT GMBH (DE) | 2001-01-18 | — | — | WO | claimed |
| US-6084114-A | Dipalladaphosphacyclobutanes and a process for preparing the same | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2000-07-04 | — | — | US | claimed |
| EP-0938490-A1 | NEW DIPALLADAPHOSPHACYCLOBUTANES AND A PROCESS FOR PREPARING THE SAME | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-09-01 | — | — | EP | claimed |
| EP-0938459-A1 | PROCESS FOR PREPARING AROMATIC OLEFINS BY USING PALLADAPHOSPHACYCLOBUTANES AS CATALYSTS | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-09-01 | — | — | EP | claimed |
| WO-1998022412-A1 | PROCESS FOR PREPARING AROMATIC OLEFINS BY USING PALLADAPHOSPHACYCLOBUTANES AS CATALYSTS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1998-05-28 | — | — | WO | claimed |
| WO-1998022485-A1 | NEW DIPALLADAPHOSPHACYCLOBUTANES AND A PROCESS FOR PREPARING THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1998-05-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170368039-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | PGR 2952/4885AR 2931/4885NPSR1 688/4885 |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | PGR 2203/4885AR 1175/4885NPSR1 123/4885 |
| US-10772874-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | PGR 1996/4885AR 1874/4885NPSR1 1134/4885 |
| US-10272072-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | PGR 1996/4885AR 1874/4885NPSR1 1134/4885 |
| US-11802111-B2 | Cyclobutyl amide monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | PGR 2227/4885AR 1147/4885NPSR1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.