SCHEMBL1609982

SCHEMBL1609982

Cn1c2ccccc2c2cncnc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.52
DDB1 Q16531 1/20 0.45
CRBN Q96SW2 1/20 0.45
PDE10A Q9Y233 6/20 0.44
TOP2A P11388 1/20 0.44
LIMK1 P53667 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628323 0.82 TOP2A (0.41) PDE10ATOP2ACYP1A2CYP3A4TSHR
SCHEMBL2628309 0.81 ADORA3 (0.40) PDE10ATOP2ACYP1A2CYP3A4TSHR
SCHEMBL13172843 0.80 PI4KA (0.41) CYP1A2CYP3A4TSHRCLK4SMN1; SMN2
SCHEMBL9211857 0.79 DDB1 (0.45) GPR3DDB1CRBNCYP1A2CYP3A4
SCHEMBL21579481 0.79 DDB1 (0.45) GPR3DDB1CRBNCYP1A2CYP3A4
SCHEMBL2628310 0.79 FEN1 (0.45) PDE10ATOP2ACYP1A2CYP3A4TSHR
SCHEMBL19009221 0.78 PTGER4 (0.59) DDB1CRBNCYP1A2TSHRLMNA
SCHEMBL2628356 0.78 MAPK14 (0.42) PDE10ATOP2ACYP1A2CYP3A4TSHR
SCHEMBL18237473 0.78 TSHR (0.50) GPR3DDB1CRBNPDE10ACYP1A2
SCHEMBL12396569 0.76 KDM4E (0.55) DDB1CRBNCYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11731990-B2 Carbazole-based Bodipys for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11731990-B2 Carbazole-based Bodipys for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11056656-B2 Organoboron complexes and their use in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-07-06 US disclosed
EP-3621971-B1 CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20210079024-A1 CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-03-18 US disclosed
EP-3621970-B1 ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-13 EP disclosed
US-20200388761-A1 ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-12-10 US disclosed
EP-3541890-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-10-28 EP disclosed
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-11-21 US disclosed
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-08-29 US disclosed
US-8114530-B2 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-02-14 US disclosed
US-8114530-B2 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-02-14 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20090066226-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-12 US disclosed
US-20090066226-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-12 US disclosed
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11056656-B2 Organoboron complexes and their use in organic electroluminescent devices NDUFC1, MT-ND6, NDUFC2 GPR3 3243/4885DDB1 1143/4885CRBN 4278/4885
US-20200388761-A1 ORGANOBORON COMPLEXES FOR ORGANIC ELECTROLUMINESCENT DEVICES NDUFC1, KCNC1, MT-ND6 GPR3 3473/4885DDB1 1200/4885CRBN 4300/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L GPR3 3325/4885DDB1 1227/4885CRBN 2567/4885
US-20210079024-A1 CARBAZOLE-BASED BODIPYS FOR ORGANIC ELECTROLUMINESCENT DEVICES CYP1B1, ECI1, FIS1 GPR3 641/4885DDB1 1214/4885CRBN 2658/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L GPR3 2959/4885DDB1 1722/4885CRBN 2452/4885
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME ICMT, ORAI2, ILK GPR3 4514/4885DDB1 2849/4885CRBN 4420/4885
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS POLRMT, EIF2AK2, NSUN3 GPR3 4732/4885DDB1 678/4885CRBN 2790/4885
US-20190352318-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM GPR3 4018/4885DDB1 2177/4885CRBN 4072/4885
US-11731990-B2 Carbazole-based Bodipys for organic electroluminescent devices CYP1B1, ECI1, FIS1 GPR3 641/4885DDB1 1214/4885CRBN 2658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.