Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | PHGDH | O43175 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963209 | 0.94 | ALDH1A1 (0.59) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL3082737 | 0.83 | ALDH1A1 (0.61) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL1615888 | 0.81 | TAS2R38 (0.60) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL2888642 | 0.80 | HPGD (0.55) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL28728362 | 0.79 | ALDH1A1 (0.56) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL11222830 | 0.79 | ALDH1A1 (0.61) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL465265 | 0.79 | HPGD (0.73) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL27633944 | 0.78 | CYP1A2 (0.69) | HPGDALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL11593786 | 0.78 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CYP1A2GAANPC1 | |
| SCHEMBL1006629 | 0.77 | ALDH1A1 (0.54) | TAS2R38HPGDALDH1A1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563446-A | ANTICOAGULANT, ANTISCHEMIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-07 | — | — | US | claimed |
| CN-111320562-B | Method for producing isothiocyanate | 旭化成株式会社 | 2022-08-16 | — | — | CN | disclosed |
| CN-113880741-A | Method for producing isothiocyanate | 旭化成株式会社 | 2022-01-04 | — | — | CN | disclosed |
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-10-21 | — | — | US | disclosed |
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | UNIV TEXAS (US) | 2021-09-30 | — | — | US | disclosed |
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| EP-3363785-B1 | ISOTHIOCYANATE PRODUCTION METHODS | ASAHI CHEMICAL IND (JP) | 2020-09-16 | — | — | EP | disclosed |
| CN-111320562-A | Method for producing isothiocyanate | 旭化成株式会社 | 2020-06-23 | — | — | CN | disclosed |
| US-10597421-B2 | Protected monomer and method of final deprotection for RNA synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-08-01 | — | — | US | disclosed |
| US-20120184724-A1 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110190296-A1 | Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2011-08-04 | — | — | US | disclosed |
| US-20110190369-A1 | Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2011-08-04 | — | — | US | disclosed |
| EP-2319843-A1 | Substituted pyrrole derivatives and their use as HMG-CO inhibitors | Ranbaxy Laboratories Limited (IN) | 2011-05-11 | — | — | EP | disclosed |
| US-7923467-B2 | Substituted pyrrole derivatives and their use as HMG-CO inhibitors | Ranbaxy Laboratories, Inc. (IN) | 2011-04-12 | — | — | US | disclosed |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| US-20100056602-A1 | Substituted Pyrrole Derivatives And Their Use As HMG-CO Inhibitors | RANBAXY LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | US | disclosed |
| WO-2008022365-A2 | COMPOSITIONS FOR INFLUENCING THE EFFECTS OF ORGANOPHOSPHORUS COMPOUNDS AND USE OF GALANTHAMINE, ITS DERIVATIVES AND ANALOGUES FOR PRODUCING SUCH COMPOSITIONS | SANOCHEMIA LTD. (MT) | 2008-02-28 | — | — | WO | disclosed |
| US-4500623-A | Photoconductive compositions comprising an organic photoconductor and a thioamide compound and electrophotographic light-sensitive materials using the compositions | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056602-A1 | Substituted Pyrrole Derivatives And Their Use As HMG-CO Inhibitors | HMGCR, HMGB2, HMGB3 | TAS2R38 4794/4885HPGD 46/4885ALDH1A1 1346/4885 |
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | TAS2R38 320/4885HPGD 1222/4885ALDH1A1 723/4885 |
| US-20210323913-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | TAS2R38 1193/4885HPGD 3786/4885ALDH1A1 431/4885 |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | TST, SLCO4C1, SLCO2B1 | TAS2R38 320/4885HPGD 1222/4885ALDH1A1 723/4885 |
| US-20110190369-A1 | Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors | HMGCR, HMGB2, HMGB3 | TAS2R38 4794/4885HPGD 46/4885ALDH1A1 1346/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | TAS2R38 4144/4885HPGD 812/4885ALDH1A1 1480/4885 |
| US-10597421-B2 | Protected monomer and method of final deprotection for RNA synthesis | NSUN2, RNGTT, RNMT | TAS2R38 3612/4885HPGD 3084/4885ALDH1A1 4361/4885 |
| US-20110190296-A1 | Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors | HMGCR, HMGB2, HMGB3 | TAS2R38 4794/4885HPGD 46/4885ALDH1A1 1346/4885 |
| US-20120184724-A1 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | RNMT, RNGTT, NSUN2 | TAS2R38 3801/4885HPGD 1649/4885ALDH1A1 3173/4885 |
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | TAS2R38 1143/4885HPGD 3645/4885ALDH1A1 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.