Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164271 | 0.86 | KDM4E (0.47) | ALOX5HPGDMAPTMEN1NR1I2 | |
| SCHEMBL3897112 | 0.73 | L3MBTL1 (0.43) | HPGDMAPTMTNR1ATRPA1PTGES | |
| SCHEMBL16166295 | 0.69 | ALOX5 (0.40) | ALOX5MEN1KMT2APTGESPTPN1 | |
| SCHEMBL5166899 | 0.69 | TRPA1 (0.44) | ALOX5HPGDADRA1AMTNR1ATRPA1 | |
| SCHEMBL8889572 | 0.68 | MTNR1A (0.36) | HPGDMAPTMTNR1ATRPA1PTGES | |
| SCHEMBL16166184 | 0.68 | HTT (0.43) | ALOX5HPGDMEN1CNR1KMT2A | |
| SCHEMBL3953509 | 0.68 | ALOX5 (0.56) | ALOX5HPGDMAPTMEN1NR1I2 | |
| SCHEMBL5163415 | 0.68 | NDUFS8 (0.47) | HPGDMAPTMEN1NR1I2LMNA | |
| SCHEMBL3901893 | 0.67 | ALOX5 (0.58) | ALOX5HPGDMAPTMEN1NR1I2 | |
| SCHEMBL5166963 | 0.67 | TRPA1 (0.45) | HPGDADRA1AMTNR1ATRPA1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984072-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | Universita Di Pisa (IT) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167481-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | UNIVERSITA' DI PISA (IT) | 2014-10-16 | — | — | WO | disclosed |