Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837925 | 1.00 | SLC6A4 (0.46) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL636461 | 1.00 | SLC6A4 (0.46) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL30664386 | 0.98 | SLC6A4 (0.44) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL10038034 | 0.93 | ACHE (0.52) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL16329073 | 0.93 | ACHE (0.52) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL14596128 | 0.86 | SLC6A4 (0.47) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL635988 | 0.86 | SLC6A4 (0.47) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL5124406 | 0.84 | SLC6A4 (0.43) | SLC6A4CA12CA1CA2CA7 | |
| SCHEMBL1466083 | 0.82 | ALDH1A1 (0.42) | SLC6A4ALDH1A1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8653942 | 0.82 | SLC6A4 (0.46) | SLC6A4MAOAMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117902990-A | Preparation method of ilalastine intermediate (R) -6- (2-amino-4-methoxyphenyl) -5,6,7, 8-tetrahydronaphthalene-2-ol | 海化生命(厦门)科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-20160175829-A1 | CATALYST SYSTEMS FOR USE IN CONTINUOUS FLOW REACTORS AND METHODS OF MANUFACTURE AND USE THEREOF | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-06-23 | — | — | US | claimed |
| EP-2264000-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND USING RUTHENIUM COMPOUND | NIPPON SODA CO (JP) | 2016-05-11 | — | — | EP | claimed |
| EP-1927596-B9 | DIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX USING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2013-05-15 | — | — | EP | claimed |
| EP-1927596-B1 | DIPHOSPHINE LIGAND AND TRANSITION METAL COMPLEX USING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2012-08-01 | — | — | EP | claimed |
| US-8207379-B2 | Ruthenium compound and method for producing optically active aminoalcohol compound | NIPPON SODA CO., LTD. (JP) | 2012-06-26 | — | — | US | claimed |
| EP-2420507-A1 | Diphosphine ligand and transition metal complex using the same | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | claimed |
| US-20110028749-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | NIPPON SODA CO., LTD. (JP) | 2011-02-03 | — | — | US | claimed |
| EP-2264000-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | Nippon Soda Co., Ltd. (JP) | 2010-12-22 | — | — | EP | claimed |
| US-20100311975-A1 | CATIONIC TRANSITION METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-12-09 | — | — | US | claimed |
| EP-1674465-A1 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-28 | — | — | EP | claimed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | claimed |
| US-6979742-B1 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-12-27 | — | — | US | claimed |
| US-6790973-B2 | REDUCTION OF KETONE TO ALCOHOL USING COMPLEX CATALYST | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2004-09-14 | — | — | US | claimed |
| US-20030166978-A1 | Novel ruthenium complexes and process for preparing alcoholic compounds using these | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2003-09-04 | — | — | US | claimed |
| EP-1323724-A2 | Novel ruthenium complexes and process for preparing alcoholic compounds using these | Kanto Kagaku Kabushiki Kaisha (JP) | 2003-07-02 | — | — | EP | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0912467-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| US-5763688-A | HYDROGENATING A CARBONYL COMPOUND, RUTHENIUM-PHOSPHINE COMPLEX CATALYST, BASE, DIAMINE | RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) | 1998-06-09 | — | — | US | claimed |
| WO-1998000375-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1998-01-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175829-A1 | CATALYST SYSTEMS FOR USE IN CONTINUOUS FLOW REACTORS AND METHODS OF MANUFACTURE AND USE THEREOF | TKFC, F2, PICALM | SLC6A4 4138/4885CA12 197/4885CA1 234/4885 |
| US-20100311975-A1 | CATIONIC TRANSITION METAL CATALYSTS | AP2M1, OPRM1, CD81 | SLC6A4 1993/4885CA12 2196/4885CA1 2319/4885 |
| US-20110028749-A1 | RUTHENIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL COMPOUND | PDHX, PKLR, RIOX2 | SLC6A4 3579/4885CA12 4478/4885CA1 3853/4885 |
| US-20030166978-A1 | Novel ruthenium complexes and process for preparing alcoholic compounds using these | ADH1C, ADH1A, ADH5 | SLC6A4 4133/4885CA12 2275/4885CA1 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.