SCHEMBL16289366

SCHEMBL16289366

[CH2]c1ccc2cc(S(C)(=O)=O)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.49
AKR1C2 P52895 2/20 0.49
ATM Q13315 1/20 0.45
PTGS2 P35354 2/20 0.42
ENPP2 Q13822 2/20 0.40
G6PD P11413 1/20 0.40
IDE P14735 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.36
KDM2B Q8NHM5 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12508320 0.87 AKR1C3 (0.58) AKR1C3AKR1C2ATMPTGS2ENPP2
SCHEMBL13203351 0.80 AKR1C3 (0.52) AKR1C3AKR1C2ATMPTGS2ENPP2
SCHEMBL758323 0.78 ATM (0.66) AKR1C3AKR1C2ATMPTGS2L3MBTL1
SCHEMBL28027 0.77 ENPP2 (0.56) PTGS2ENPP2
SCHEMBL12267631 0.77 CYP2A6 (0.56) AKR1C3AKR1C2ATMPTGS2SMN1; SMN2
SCHEMBL15624757 0.77 ATM (0.59) AKR1C3AKR1C2ATMPTGS2L3MBTL1
SCHEMBL3883747 0.75 AKR1C3 (0.49) AKR1C3AKR1C2ATMPTGS2ENPP2
SCHEMBL10484185 0.75 AKR1C3 (0.49) AKR1C3AKR1C2ATMPTGS2G6PD
SCHEMBL8035317 0.75 ENPP2 (0.61) AKR1C3AKR1C2ATMPTGS2ENPP2
SCHEMBL16289803 0.74 NPBWR1 (0.39) AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-01 US disclosed
EP-2813492-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL Sumitomo Chemical Co., Ltd (JP) 2014-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 AKR1C3 564/4885AKR1C2 1277/4885ATM 2127/4885
US-20150005348-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL RPS8, MT-CO2, ARG1 AKR1C3 527/4885AKR1C2 1095/4885ATM 1412/4885
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 AKR1C3 470/4885AKR1C2 1437/4885ATM 4707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.