Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fomesafen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TTR | P02766 | 1/20 | 0.67 |
| ▸ | PPOX | P50336 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fomesafen SCHEMBL29729477 | 1.00 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL8582624 | 0.86 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11004074 | 0.85 | MEN1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL21658822 | 0.85 | TDP1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL39453 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL30370086 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29352750 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29471425 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL466794 | 0.83 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| Fomesafen SCHEMBL527125 | 0.83 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2234 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060254-A1 | HERBICIDAL COMPOSITIONS | BAYER AG (DE) | 2026-03-05 | — | — | US | claimed |
| US-20260020563-A1 | METHOD FOR CONTROLLING PESTS OF FARM CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-01-22 | — | — | US | claimed |
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| US-20250318528-A1 | HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-10-16 | — | — | US | claimed |
| EP-4577047-A1 | HERBICIDAL COMPOSITIONS | Bayer Aktiengesellschaft (DE) | 2025-07-02 | — | — | EP | claimed |
| US-20250185661-A1 | METHOD FOR CONTROLLING WEEDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-06-12 | — | — | US | claimed |
| CN-119744118-A | Herbicidal composition | 拜耳公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119138410-A | Synergistic auxiliary agent for fomesafen sodium salt aqueous agent and preparation process thereof | 南京凯元新材料科技有限公司 | 2024-12-17 | — | — | CN | claimed |
| US-20240349725-A1 | FORMULATION COMPRISING AN ACID FUNCTION ACTIVE INGREDIENT, ESTER FUNCTION ACTIVE INGREDIENT AND SALT AND/OR CHEMICALLY LABILE ACTIVE INGREDIENT, THE USE THEREOF AND METHOD OF PRODUCTION | IHARABRAS S A INDUSTRIAS QUIM (BR) | 2024-10-24 | — | — | US | claimed |
| WO-2024041926-A1 | HERBICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-29 | — | — | WO | claimed |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-03 | — | — | US | claimed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | claimed |
| CN-102404991-A | Herbicidal formulations | SYNGENTA LTD | 2012-04-04 | — | — | CN | claimed |
| WO-2011086576-A2 | AN ORGANIZED LIQUID MIXTURE | UNITED PHOSPHORUS LIMITED (IN) | 2011-07-21 | — | — | WO | claimed |
| WO-2010143205-A2 | HERBICIDAL COMPOSITION | UNITED PHOSPHORUS LIMITED (IN) | 2010-12-16 | — | — | WO | claimed |
| US-20100099563-A1 | HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-04-22 | — | — | US | claimed |
| EP-2106697-A1 | HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-10-07 | — | — | EP | claimed |
| WO-2009007013-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC 3-(2-ALKOXY-4-CHLORO-6-ALKYL-PHENYL)-SUBSTITUTED TETRAMATES | BAYER CROPSCIENCE AG (DE) | 2009-01-15 | — | — | WO | claimed |
| EP-2014170-A1 | Herbicide combinations with special 3-(2-alkoxy 4-chlorine-6-alkyl-phenyl) substituted tetramates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | claimed |
| CN-1276154-A | Emulsifiable concentrate or powder of fomesafen and chlorimuron-ethyl | ZHANG BAIFENG (CN) | 2000-12-13 | — | — | CN | claimed |