Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fomesafen. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | PPOX | P50336 | 1/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fomesafen SCHEMBL466794 | 0.85 | TDP1 (0.70) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9720252 | 0.85 | TDP1 (0.86) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11004074 | 0.85 | MEN1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL39453 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL6752643 | 0.84 | MEN1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL3690938 | 0.84 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29352750 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29471425 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL30370086 | 0.84 | TDP1 (0.82) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9755520 | 0.84 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337017-A1 | HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS | Bayer Aktiengesellschaft (DE) | 2024-03-20 | — | — | EP | claimed |
| WO-2022152728-A1 | HERBICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-07-21 | — | — | WO | claimed |
| WO-2026098491-A1 | TRANSGENIC GLYCINE MAX EVENT KA-6G2Ø16-7 AND DETECTION METHOD THEREFOR | 青岛清原种子科学有限公司 | 2026-05-15 | — | — | WO | disclosed |
| CN-118266468-B | Weeding composition containing protoporphyrinogen oxidase inhibitor and application thereof | 青岛恒宁生物科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4617275-A1 | OXABICYCLOALKANE COMPOUNDS, PREPARATION METHOD THEREFOR, AND HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2025-09-17 | — | — | EP | disclosed |
| US-20250230462-A1 | PPO2 POLYPEPTIDE HAVING TOLERANCE TO PPO INHIBITOR HERBICIDE AND APPLICATION | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2025-07-17 | — | — | US | disclosed |
| WO-2025118900-A1 | USE OF HEMG PPO ENZYME IN GENERATING OR IMPROVING TOLERANCE TO PPO-INHIBITING HERBICIDES | 青岛清原种子科学有限公司 | 2025-06-12 | — | — | WO | disclosed |
| US-12325646-B2 | Fertigation water treatment | UNIVERSITY OF GUELPH (CA) | 2025-06-10 | — | — | US | disclosed |
| CN-120118937-A | Use of HemG PPO enzymes for producing or increasing tolerance to PPO-inhibiting herbicides | 青岛清原种子科学有限公司 | 2025-06-10 | — | — | CN | disclosed |
| US-20250024837-A1 | PESTICIDE SYSTEM | BANISH, MICHELE | 2025-01-23 | — | — | US | disclosed |
| US-20240368618-A1 | PPO POLYPEPTIDES TOLERANT TO PPO-INHIBITING HERBICIDES AND USE THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2024-11-07 | — | — | US | disclosed |
| EP-2196089-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-16 | — | — | EP | disclosed |
| EP-2196088-A1 | Fungicidal Compositions | Syngenta Participations AG (CH) | 2010-06-16 | — | — | EP | disclosed |
| EP-2193715-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193714-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193717-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193716-A1 | Fungicidal Compositions | Syngenta Participations AG (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2150113-A1 | FUNGICIDAL COMPOSITIONS | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008131901-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | disclosed |
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | ENPP1, ENPP3, SMPD1 | THRB 4526/4885TDP1 696/4885MEN1 1618/4885 |
| US-20250024837-A1 | PESTICIDE SYSTEM | ACHE, PFAS, FPGS | THRB 4104/4885TDP1 100/4885MEN1 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.