Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913036 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL30006581 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL11197203 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL31629817 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL14735789 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL1686159 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL7989065 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL19889196 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL20946304 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1USP2SLCO1B1 | |
| SCHEMBL19889263 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053044-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | UNIV EMORY (US) | 2021-02-25 | — | — | US | disclosed |
| US-20180318818-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | EMORY UNIVERSITY (US) | 2018-11-08 | — | — | US | disclosed |
| US-9700881-B2 | Heterocyclic coupling catalysts and methods related thereto | EMORY UNIVERSITY (US) | 2017-07-11 | — | — | US | disclosed |
| WO-2017070157-A1 | REDOX DEHYDRATION COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20160243534-A1 | Heterocyclic Coupling Catalysts and Methods Related Thereto | EMORY UNIVERSITY (US) | 2016-08-25 | — | — | US | disclosed |
| US-9382193-B2 | Processes for forming amide bonds and compositions related thereto | EMORY UNIVERSITY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150315129-A1 | PROCESSES FOR FORMING AMIDE BONDS AND COMPOSITIONS RELATED THERETO | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-05 | — | — | US | disclosed |
| US-20150209477-A1 | COMPOSITIONS FOR BIOMEDICAL APPLICATIONS | UNIV MASSACHUSETTS MEDICAL (US) | 2015-07-30 | — | — | US | disclosed |
| WO-2015054337-A1 | HETEROCYCLIC COUPLING CATALYSTS AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2015-04-16 | — | — | WO | disclosed |
| US-8921599-B2 | Processes for forming amide bonds and compositions related thereto | EMORY UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20110104076-A1 | Compositions, Methods For Preparing Amino Acids And Nuclear Magnetic Resonance Spectroscopy | GLYCONIX CORPORATION | 2011-05-05 | — | — | US | disclosed |
| US-20100159011-A1 | Compositions For Biomedical Applications | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 2010-06-24 | — | — | US | disclosed |
| EP-2184995-A2 | COMPOSITES FOR BIOMEDICAL APPLICATIONS | University of Massachusetts Medical School (US) | 2010-05-19 | — | — | EP | disclosed |
| EP-2178936-A1 | POLYMER COMPOSITIONS FOR BIOMEDICAL AND MATERIAL APPLICATIONS | University of Massachusetts Medical School (US) | 2010-04-28 | — | — | EP | disclosed |
| US-20100098761-A1 | Polymer Compositions For Biomedical And Material Applications | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 2010-04-22 | — | — | US | disclosed |
| WO-2009025719-A1 | POLYMER COMPOSITIONS FOR BIOMEDICAL AND MATERIAL APPLICATIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009020550-A2 | COMPOSITES FOR BIOMEDICAL APPLICATIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2007070195-A2 | COMPOSITIONS, METHODS OF PREPARING AMINO ACIDS AND NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | GLYCONIX CORPORATION (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070104648-A1 | Compositions, methods of preparing amino acids, and nuclear magnetic resonance spectroscopy | GLYCONIX CORPORATION | 2007-05-10 | — | — | US | disclosed |
| US-20070037756-A1 | Compositions and methods for the prevention and treatment of circulatory conditions | LEADTREK, INC (US) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315129-A1 | PROCESSES FOR FORMING AMIDE BONDS AND COMPOSITIONS RELATED THERETO | TMT1A, LPO, GSTO1 | TDP1 1002/4885LMNA 3649/4885L3MBTL1 1268/4885 |
| US-20160243534-A1 | Heterocyclic Coupling Catalysts and Methods Related Thereto | HAT1, CBR3, CBR1 | TDP1 2995/4885LMNA 4018/4885L3MBTL1 2888/4885 |
| US-20110104076-A1 | Compositions, Methods For Preparing Amino Acids And Nuclear Magnetic Resonance Spectroscopy | BCAT1, BCAT2, SLC3A2 | TDP1 3046/4885LMNA 1950/4885L3MBTL1 1227/4885 |
| US-20180318818-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | SCLY, TST, SELENOI | TDP1 2232/4885LMNA 4270/4885L3MBTL1 2620/4885 |
| US-20070104648-A1 | Compositions, methods of preparing amino acids, and nuclear magnetic resonance spectroscopy | BCAT1, BCAT2, SLC3A2 | TDP1 3162/4885LMNA 2448/4885L3MBTL1 1469/4885 |
| US-20070037756-A1 | Compositions and methods for the prevention and treatment of circulatory conditions | SELP, PTGER3, PLTP | TDP1 1900/4885LMNA 2111/4885L3MBTL1 3234/4885 |
| US-20100159011-A1 | Compositions For Biomedical Applications | ILK, MATR3, ECPAS | TDP1 2342/4885LMNA 379/4885L3MBTL1 3255/4885 |
| US-20210053044-A1 | Redox Dehydration Coupling Catalysts and Methods Related Thereto | SCLY, TST, SQOR | TDP1 2242/4885LMNA 4184/4885L3MBTL1 2808/4885 |
| US-20100098761-A1 | Polymer Compositions For Biomedical And Material Applications | ILK, ECPAS, PTH1R | TDP1 2038/4885LMNA 357/4885L3MBTL1 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.