Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 1.00 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.70 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.65 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719560 | 0.88 | MPO (0.79) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| SCHEMBL29504999 | 0.88 | MPO (0.79) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| SCHEMBL1463277 | 0.86 | GRIK1 (0.82) | MPOAKR1C3AKR1C2GRIK1RXFP1 | |
| SCHEMBL23691075 | 0.85 | MPO (0.76) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| SCHEMBL29504977 | 0.85 | MPO (0.74) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| SCHEMBL22719595 | 0.85 | MPO (0.74) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| Flufenamic Acid SCHEMBL29356958 | 0.83 | RXFP1 (0.75) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| Flufenamic Acid SCHEMBL17497 | 0.83 | RXFP1 (0.75) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| Flufenamic Acid SCHEMBL9845499 | 0.82 | RXFP1 (0.73) | MPOAKR1C3AKR1C2GRIK1TAS2R14 | |
| Flufenamic Acid SCHEMBL11524554 | 0.82 | RXFP1 (0.73) | MPOAKR1C3AKR1C2GRIK1TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135864-A1 | POLLINATION IMPROVER | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-05-31 | — | — | US | disclosed |
| US-20120108431-A1 | PLANT GROWTH REGULATOR ADDITIVE | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-05-03 | — | — | US | disclosed |
| US-20120101164-A1 | ABSCISSION AND CROP STORAGE UNIT | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-04-26 | — | — | US | disclosed |
| US-20120088667-A1 | SAFENING AGENT | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101164-A1 | ABSCISSION AND CROP STORAGE UNIT | BROX, ACR, ABAT | MPO 1474/4885AKR1C3 1647/4885AKR1C2 1323/4885 |
| US-20120088667-A1 | SAFENING AGENT | PIN1, IPO11, XPO1 | MPO 2236/4885AKR1C3 783/4885AKR1C2 1055/4885 |
| US-20120135864-A1 | POLLINATION IMPROVER | AADAT, TIPARP, GSR | MPO 2574/4885AKR1C3 62/4885AKR1C2 159/4885 |
| US-20120108431-A1 | PLANT GROWTH REGULATOR ADDITIVE | MYB, ING2, AGXT | MPO 4471/4885AKR1C3 1005/4885AKR1C2 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.