Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylmethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.56 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.56 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonic Acid SCHEMBL135008 | 0.97 | CA2 (0.58) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL7208342 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL5858462 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL7098601 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL9812588 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL6959619 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL340526 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL2057826 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL18419593 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 | |
| Phenylmethanesulfonic Acid SCHEMBL1565755 | 0.95 | CA2 (0.56) | CA2CA9CA1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171483-B1 | DISSOLVABLE SOLID FIBROUS ARTICLES CONTAINING ANIONIC SURFACTANTS | PROCTER & GAMBLE (US) | 2026-04-08 | — | — | EP | claimed |
| CN-120158762-A | Ruthenium cluster-loaded nitrogen-doped carbon-based composite catalytic material and preparation method and application thereof | 杭州师范大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119735535-A | Synthesis method and application of electrophilic selenium deuterated methyl reagent | 杭州师范大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119371338-A | Preparation method of benzyl sulfonyl chloride | 寿光诺盟化工有限公司 | 2025-01-28 | — | — | CN | claimed |
| EP-4455262-A1 | CELL CULTURE MEMBRANE, AND METHOD FOR PRODUCING BIOLOGICAL TISSUE | Toyo Seikan Group Holdings, Ltd. (JP) | 2024-10-30 | — | — | EP | claimed |
| CN-118771794-A | Seawater and sea sand ultra-high performance concrete and preparation method and application thereof | 山东晟世达科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-20240327770-A1 | CELL CULTURE MEMBRANE AND METHOD FOR PRODUCING BIOLOGICAL TISSUE | TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) | 2024-10-03 | — | — | US | claimed |
| CN-118632900-A | Thermoplastic composition | 高新特殊工程塑料全球技术有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-118355075-A | Polycarbonate compositions | SABIC环球技术有限责任公司 | 2024-07-16 | — | — | CN | claimed |
| CN-114621833-B | Liquid phosphorus-free alkaline membrane cleaning agent and preparation method thereof | 河北源清环保科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-0479908-B1 | IMPROVED AQUEOUS CLEANER/DEGREASER COMPOSITIONS | BUCKEYE INT (US) | 1995-03-08 | — | — | EP | claimed |
| EP-0524427-A2 | Aqueous hair styling aid | HELENE CURTIS, INC. (US) | 1993-01-27 | — | — | EP | claimed |
| US-5164177-A | Aqueous aerosol or nonaerosol hair spray | HELENE CURTIS, INC. (US) | 1992-11-17 | — | — | US | claimed |
| EP-0228980-B1 | A PROCESS FOR THE PREPARATION OF HEXAMETHYL TETRACOSANES | HISPANO QUIMICA S.A. (ES) | 1989-09-13 | — | — | EP | claimed |
| EP-0074329-B1 | AQUEOUS CONCENTRATES OF PESTICIDES | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | claimed |
| EP-0153857-B1 | DETERGENT COMPOSITIONS | UNILEVER N.V. (NL) | 1988-09-21 | — | — | EP | claimed |
| EP-0268227-A2 | Method for cleaning and disinfecting endoscopes, and product for carrying out the method | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-05-25 | — | — | EP | claimed |
| US-4430236-A | MONIONIC SURFACTANT, HYDROGEN PEROYIE AND BRIGHTNER | TEXIZE, DIVISION OF MORTONTHIOKOL (US) | 1984-02-07 | — | — | US | claimed |
| EP-0074329-A2 | Aqueous concentrates of pesticides | CIBA-GEIGY AG (CH) | 1983-03-16 | — | — | EP | claimed |
| US-4255294-A | MULTIFUNCTIONAL DETERGENT COMPRISING A COMPLEX OF A CATIONIC NITROGENOUS COMPOUND AND AN ANIONIC DETERGENT USING AS A DISPERSANT A NONIONIC SURFACTANT | LEVER BROTHERS (US) | 1981-03-10 | — | — | US | claimed |