Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708332 | 0.90 | ALDH1A1 (0.32) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1707908 | 0.79 | CD274 (0.41) | RAB9APDCD1CD274MEN1KMT2A | |
| SCHEMBL1707949 | 0.79 | PDCD1 (0.36) | GAAHAO1RAB9AMAPTPDCD1 | |
| SCHEMBL1708225 | 0.76 | KLKB1 (0.35) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1708592 | 0.76 | ALDH1A1 (0.33) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10291218 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1708437 | 0.76 | PDCD1 (0.33) | HAO1NR3C1PDCD1CD274 | |
| SCHEMBL1708101 | 0.75 | RORC (0.33) | PDCD1CD274 | |
| SCHEMBL1708201 | 0.75 | PDCD1 (0.33) | ALDH1A1TDP1L3MBTL1MAPTPDCD1 | |
| SCHEMBL1707845 | 0.75 | PDCD1 (0.33) | ALDH1A1TDP1L3MBTL1MAPTPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |