Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1707867 | 0.90 | ALDH1A1 (0.40) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1707949 | 0.78 | PDCD1 (0.36) | GAAINSRIGF1RMAPTRAB9A | |
| SCHEMBL1708437 | 0.77 | PDCD1 (0.33) | NR3C1PDCD1CD274HAO1 | |
| SCHEMBL10010108 | 0.76 | FFAR1 (0.51) | FFAR1 | |
| SCHEMBL10291529 | 0.75 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL1708101 | 0.75 | RORC (0.33) | PDCD1CD274 | |
| SCHEMBL1707908 | 0.74 | CD274 (0.41) | RAB9APDCD1CD274 | |
| SCHEMBL1708201 | 0.73 | PDCD1 (0.33) | ALDH1A1TDP1L3MBTL1MAPTPDCD1 | |
| SCHEMBL1707845 | 0.73 | PDCD1 (0.33) | ALDH1A1TDP1L3MBTL1INSRIGF1R | |
| SCHEMBL1708254 | 0.72 | MAPT (0.37) | ALDH1A1GAASMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |