SCHEMBL171778

SCHEMBL171778

CC1(C)OB(c2ccc(CN)cc2)OC1(C)C

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 14/20 0.65
▸ LPL P06858 13/20 0.65
▸ F11 P03951 2/20 0.60
▸ ESR2 Q92731 1/20 0.51
▸ CA1 P00915 3/20 0.49
▸ CA2 P00918 3/20 0.49
▸ CA9 Q16790 3/20 0.49
▸ CA12 O43570 1/20 0.49
▸ CA3 P07451 1/20 0.49
▸ CA4 P22748 1/20 0.49
▸ CA6 P23280 1/20 0.49
▸ CA5A P35218 1/20 0.49
▸ CA7 P43166 1/20 0.49
▸ CA14 Q9ULX7 1/20 0.49
▸ CA5B Q9Y2D0 1/20 0.49
▸ F2 P00734 1/20 0.46
▸ PRSS1 P07477 1/20 0.46
▸ PRSS2 P07478 1/20 0.46
▸ PRSS3 P35030 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1585363 0.98 LIPG (0.62) LIPGLPLF11ESR2CA1
Hydrochloric Acid SCHEMBL101098 0.96 LIPG (0.61) LIPGLPLF11ESR2CA1
SCHEMBL23085216 0.86 LIPG (0.50) LIPGLPLF11ESR2CA1
SCHEMBL3128892 0.85 LPL (0.71) LIPGLPLF11ESR2CA1
SCHEMBL10006068 0.83 LIPG (0.81) LIPGLPLF11ESR2CA1
SCHEMBL15432466 0.83 LPL (0.69) LIPGLPLF11ESR2CA1
SCHEMBL228212 0.82 LPL (0.71) LIPGLPLF11ESR2CA1
SCHEMBL1331631 0.82 LIPG (0.63) LIPGLPLF11
SCHEMBL31329315 0.82 LPL (0.71) LIPGLPLF11ESR2CA1
SCHEMBL31329303 0.82 ESR2 (0.57) LIPGLPLF11ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739345-A1 BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME Boston Scientific Scimed, Inc. (US) 2026-05-13 — — EP disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 — — US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 — — EP disclosed
WO-2025235782-A1 BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 — — WO disclosed
US-20250345434-A1 BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 — — US disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 — — EP disclosed
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2025-10-09 — — US disclosed
US-20250295815-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF NIRVANA SCIENCES 2025-09-25 — — US disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 — — US disclosed
CN-119707886-A Preparation method of amine compound 江苏丽源医药有限公司 2025-03-28 — — CN disclosed
EP-1844019-B1 METHODE FOR THE PRODUCTION OF LOSARTAN RATIOPHARM GMBH (DE) 2009-09-02 — — EP disclosed
EP-2080756-A2 Method for making losartan Ratiopharm GmbH (DE) 2009-07-22 — — EP disclosed
US-20090111994-A1 Method for The Production of Losartan RATIOPHARM GMBH (DE) 2009-04-30 — — US disclosed
US-20090111994-A1 Method for The Production of Losartan RATIOPHARM GMBH (DE) 2009-04-30 — — US disclosed
US-20080039482-A1 SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-02-14 — — US disclosed
WO-2007147574-A1 SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-12-27 — — WO disclosed
EP-1870416-A1 Sulphonamido-macrocycles as tie2 inhibitors Bayer Schering Pharma Aktiengesellschaft (DE) 2007-12-26 — — EP disclosed
WO-2007104783-A2 1,4 -DI SUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE MGLUR2-RECEPT0R MODULATORS ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC. (US) 2007-09-20 — — WO disclosed
WO-2006081807-A2 METHOD FOR THE PRODUCTION OF LOSARTAN RATIOPHARM GMBH (DE) 2006-08-10 — — WO disclosed
US-20030232818-A1 Antibacterial compounds ABBVIE INC. 2003-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345434-A1 BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME BCCIP, BLM, BTD LIPG 432/4885LPL 3023/4885F11 1935/4885
US-20080039482-A1 SULFONAMIDO-MACROCYCLES AS TIE2 INHIBITORS AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME TIE1, KDR, TEK LIPG 82/4885LPL 1248/4885F11 225/4885
US-20090111994-A1 Method for The Production of Losartan AGTR1, REN, AGTR2 LIPG 1081/4885LPL 820/4885F11 2116/4885
US-20030232818-A1 Antibacterial compounds PGLS, UGT1A1, CASP1 LIPG 3210/4885LPL 3232/4885F11 1542/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 LIPG 249/4885LPL 178/4885F11 1186/4885
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 LIPG 3843/4885LPL 4440/4885F11 357/4885
US-12410160-B2 KHK inhibitors KHK, KHDRBS1, NADK LIPG 2261/4885LPL 3327/4885F11 4354/4885
US-20250295815-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF PPOX, PPIF, HMBS LIPG 3498/4885LPL 3774/4885F11 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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