Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15775161 | 0.98 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Hydrochloric Acid SCHEMBL15240369 | 0.98 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Hydrochloric Acid SCHEMBL1202789 | 0.98 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Bromide SCHEMBL14990906 | 0.98 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| SCHEMBL12101179 | 0.89 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Bromide SCHEMBL3309184 | 0.87 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| SCHEMBL3307726 | 0.86 | APOBEC3A (0.59) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Trifluoroacetic Acid SCHEMBL31143352 | 0.84 | HDAC2 (0.42) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Bromide SCHEMBL14990640 | 0.84 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GDRD2RAD52RECQL | |
| Bromide SCHEMBL7283805 | 0.84 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GDRD2RAD52RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073956-A1 | STING ANTAGONIST COMPOUNDS | SULIS THERAPEUTICS APS (DK) | 2025-04-10 | — | — | WO | disclosed |
| EP-4534147-A1 | STING ANTAGONIST COMPOUNDS | Sulis Therapeutics ApS (DK) | 2025-04-09 | — | — | EP | disclosed |
| CN-113382767-B | Urea compounds having substituents | 第一三共株式会社 | 2024-12-24 | — | — | CN | disclosed |
| US-12139498-B1 | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2024-11-12 | — | — | US | disclosed |
| US-20240368188-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2024-11-07 | — | — | US | disclosed |
| US-20240025924-A1 | HETEROCYCLE SUBSTITUTED KETONE DERIVATIVE, AND COMPOSITION AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| WO-2024010761-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| CN-116178361-A | Preparation of piperidine bisoxadiazole and piperidine amino thiazole substituted antitumor curcumenol derivatives and application thereof in antitumor | 华东理工大学 | 2023-05-30 | — | — | CN | disclosed |
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | SPRING MILL PHARMA, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230052191-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2023-02-16 | — | — | US | disclosed |
| US-20040019079-A1 | Beta3-Adrenoreceptor agonists, agonist compositions and methods of using | FELLER DENNIS R (US) | 2004-01-29 | — | — | US | disclosed |
| EP-1023269-A4 | BETA3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING | MOLECULAR DESIGN INT (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1023269-A1 | BETA3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING | MOLECULAR DESIGN INTERNATIONAL, INC. (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999016752-A1 | β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING | MOLECULAR DESIGNS INTERNATIONAL, INC. (US) | 1999-04-08 | — | — | WO | disclosed |
| EP-0321191-B1 | Heterocyclic-substituted quinoline-carboxylic acids | PFIZER (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5214051-A | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5037834-A | Heterocycylic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1991-08-06 | — | — | US | disclosed |
| WO-1989005643-A1 | HETEROCYCLIC-SUBSTITUTED QUINOLINE-CARBOXYLIC ACIDS | PFIZER INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| EP-0321191-A2 | Heterocyclic-substituted quinoline-carboxylic acids | PFIZER INC. (US) | 1989-06-21 | — | — | EP | disclosed |
| US-4624956-A | Ulcer and gastric secretion inhibiting 4,5,6,7-tetrahydrothiazole[5,4-c]pyridine derivatives | FARMITALIA CARLO ERBA (IT) | 1986-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025924-A1 | HETEROCYCLE SUBSTITUTED KETONE DERIVATIVE, AND COMPOSITION AND MEDICINAL USE THEREOF | BCKDK, CYP11B2, HSD17B7 | APOBEC3A 2448/4885APOBEC3G 2724/4885DRD2 2312/4885 |
| US-20230062975-A1 | HEPATITIS B CAPSID ASSEMBLY MODULATORS | HAVCR2, COPB1, HDLBP | APOBEC3A 2278/4885APOBEC3G 2536/4885DRD2 4864/4885 |
| US-20240368188-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM4, CHRM5, CHRM1 | APOBEC3A 3913/4885APOBEC3G 3584/4885DRD2 190/4885 |
| US-12139498-B1 | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 | CHRM4, CHRM5, CHRM1 | APOBEC3A 3867/4885APOBEC3G 3462/4885DRD2 197/4885 |
| US-20230052191-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | APOBEC3A 2671/4885APOBEC3G 1936/4885DRD2 3354/4885 |
| US-20040019079-A1 | Beta3-Adrenoreceptor agonists, agonist compositions and methods of using | ADRB3, ADRB1, ADRB2 | APOBEC3A 1010/4885APOBEC3G 990/4885DRD2 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.