SCHEMBL17213626

SCHEMBL17213626

C=C(C)C(=O)NCCCNC(=O)CCCn1cnc2cc3ncn(CCCC(=O)NCCCNC(=O)C(=C)C)c3cc21

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 2/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
HDAC1 Q13547 4/20 0.40
CASP1 P29466 1/20 0.37
KMT2A Q03164 2/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.34
GUSB P08236 1/20 0.34
TNF P01375 1/20 0.34
MAPK1 P28482 1/20 0.34
PLAA Q9Y263 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433632 0.76 EGLN3 (0.52) MAPTALDH1A1LMNAHTTMAPK1
SCHEMBL16309303 0.72 FAAH (0.46) POLBKMT2AMEN1
SCHEMBL19198443 0.71 IDE (0.51) ALDH1A1POLBLMNAKMT2AMEN1
SCHEMBL8943380 0.68 FAAH (0.46) MAPTALDH1A1POLBKMT2AMEN1
SCHEMBL16798934 0.68 CASP2 (0.52)
SCHEMBL21669765 0.68 TBXAS1 (0.52) ALDH1A1POLBLMNAMAPK1
SCHEMBL3069367 0.68 PTGS1 (0.49) MAPTALDH1A1LMNAKMT2ATP53
SCHEMBL21669744 0.68 TBXAS1 (0.54) ALDH1A1POLBLMNAMAPK1
SCHEMBL21669740 0.68 TBXAS1 (0.54) ALDH1A1POLBLMNAMAPK1
SCHEMBL21669747 0.68 TBXAS1 (0.54) ALDH1A1POLBLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
US-20200371062-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2020-11-26 US disclosed
US-10761053-B2 Non-enzymatic electrochemical sensor for measuring analytes TERUMO KABUSHIKI KAISHA (JP) 2020-09-01 US disclosed
EP-3498718-B1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO CORP (JP) 2020-04-15 EP disclosed
EP-3498718-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES Terumo Kabushiki Kaisha (JP) 2019-06-19 EP disclosed
EP-3134419-B1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO CORP (JP) 2019-03-13 EP disclosed
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2017-08-03 US disclosed
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES TERUMO KABUSHIKI KAISHA (JP) 2017-08-03 US disclosed
WO-2015164578-A9 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES GLUCOVATION, INC. (US) 2016-02-18 WO disclosed
WO-2015164578-A2 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES GLUCOVATION, INC. (US) 2015-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019396-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, SRR, BLVRB MAPT 4808/4885ALDH1A1 1305/4885POLB 1988/4885
US-20200371062-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES XDH, SPR, BLVRB MAPT 4832/4885ALDH1A1 753/4885POLB 1549/4885
US-20170219521-A1 NON-ENZYMATIC ELECTROCHEMICAL SENSOR FOR MEASURING ANALYTES SPR, BLVRB, XDH MAPT 4842/4885ALDH1A1 418/4885POLB 1646/4885
US-10761053-B2 Non-enzymatic electrochemical sensor for measuring analytes XDH, SPR, BLVRB MAPT 4830/4885ALDH1A1 529/4885POLB 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.