SCHEMBL1734015

SCHEMBL1734015

CC(C)(C)C(P)(c1ccccc1CP(C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2)C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14949938 0.84 CNR2 (0.35)
SCHEMBL14949926 0.82
SCHEMBL3826384 0.82
SCHEMBL14949936 0.82 SIGMAR1 (0.31)
SCHEMBL1952223 0.82 SIGMAR1 (0.33) P2RX7
SCHEMBL3000948 0.80
SCHEMBL20970168 0.80
SCHEMBL16524440 0.79 ALDH1A1 (0.32) P2RX7
SCHEMBL1734830 0.79 P2RX7 (0.39) P2RX7
SCHEMBL3000956 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794548-B1 A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE LUCITE INT UK LTD (GB) 2019-05-15 EP claimed
US-9382190-B2 Continuous process for the carbonylation of ethylene LUCITE INTERNATIONAL UK LIMITED (GB) 2016-07-05 US claimed
US-20150099896-A1 CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE LUCITE INTERNATIONAL UK LIMITED (GB) 2015-04-09 US claimed
EP-1931471-B1 CONTINUOUS CARBONYLATION PROCESS LUCITE INT UK LTD (GB) 2014-10-01 EP claimed
EP-2007703-B1 METAL COMPLEXES FOR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS LUCITE INT UK LTD (GB) 2013-12-18 EP claimed
US-8604236-B2 Catalyst system LUCITE INTERNATIONAL UK LIMITED (GB) 2013-12-10 US claimed
US-8445711-B2 Metal complexes LUCITE INTERNATIONAL UK LIMITED (GB) 2013-05-21 US claimed
US-20100197958-A1 PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM LUCITE INTERNATIONAL UK LIMITED (GB) 2010-08-05 US claimed
US-20090312561-A1 METAL COMPLEXES LUCITE INTERNATIONAL UK LIMITED (GB) 2009-12-17 US claimed
US-20090216041-A1 Catalyst System LUCITE INTERNATIONAL UK LIMITED (GB) 2009-08-27 US claimed
EP-2513031-B1 A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE LUCITE INT UK LTD (GB) 2018-08-22 EP disclosed
US-9382190-B2 Continuous process for the carbonylation of ethylene LUCITE INTERNATIONAL UK LIMITED (GB) 2016-07-05 US disclosed
US-9138694-B2 Mixing apparatus LUCITE INTERNATIONAL UK LIMITED (GB) 2015-09-22 US disclosed
EP-1931471-B1 CONTINUOUS CARBONYLATION PROCESS LUCITE INT UK LTD (GB) 2014-10-01 EP disclosed
US-8785678-B2 Continuous process for the carbonylation of ethylene LUCITE INTERNATIONAL UK LIMITED (GB) 2014-07-22 US disclosed
US-20090216041-A1 Catalyst System LUCITE INTERNATIONAL UK LIMITED (GB) 2009-08-27 US disclosed
US-20090208390-A1 MIXING APPARATUS LUCITE INTERNATIONAL UK LIMITED (GB) 2009-08-20 US disclosed
WO-2008075108-A1 CARBONYLATION OF CONJUGATED DIENES LUCITE INTERNATIONAL UK LIMITED (GB) 2008-06-26 WO disclosed
EP-1931471-A1 IMPROVED CATALYST SYSTEM Lucite International UK Limited (GB) 2008-06-18 EP disclosed
WO-2007020379-A1 IMPROVED CATALYST SYSTEM LUCITE INTERNATIONAL UK LIMITED (GB) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099896-A1 CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE SCD, ELOVL6, ALK P2RX7 4835/4885
US-20090216041-A1 Catalyst System CBS, SMS, POF1B P2RX7 4126/4885
US-20100197958-A1 PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM ALOX5, ACSL5, ELOVL5 P2RX7 2931/4885
US-20090312561-A1 METAL COMPLEXES MLX, PICALM, AP2M1 P2RX7 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.