SCHEMBL17367236

SCHEMBL17367236

CC1(C)c2ccccc2-c2oc3c(ccc4c5ccccc5[nH]c43)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.41
PARP14 Q460N5 9/20 0.37
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRG1 Q8N1C3 2/20 0.37
GABRG3 Q99928 2/20 0.37
GABRQ Q9UN88 2/20 0.37
PGR P06401 1/20 0.37
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30631795 1.00 KIF11 (0.41) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL1707718 0.78 KIF11 (0.47) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL29819516 0.78 KIF11 (0.47) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL19887076 0.77 ABCG2 (0.40) MAPTMEN1MAPK1KMT2AKDM4E
SCHEMBL15434247 0.76 KIF11 (0.45) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL17367233 0.75 CRHBP (0.32)
SCHEMBL17299583 0.73 KIF11 (0.45) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL15434242 0.73 PGR (0.43) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL18688073 0.73 GABRP (0.44) KIF11PARP14GABRPGABRDGABRA1
SCHEMBL18488873 0.73 KIF11 (0.55) KIF11PARP14GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244465-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-04-20 EP disclosed
EP-3176845-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-03-16 EP disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11217754-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2022-01-04 US disclosed
EP-3389106-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-12-01 EP disclosed
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-10505119-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-12-10 US disclosed
US-10424742-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-24 US disclosed
US-20180362843-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-12-20 US disclosed
EP-3389106-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2018-10-17 EP disclosed
US-20180212153-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-07-26 US disclosed
US-9905775-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-20180026198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-25 US disclosed
US-20170358753-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-12-14 US disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244465-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-21 US disclosed
EP-3176845-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170358753-A1 ORGANIC ELECTROLUMINESCENT DEVICE INMT, TYR, EML4 KIF11 600/4885PARP14 2130/4885GABRP 3926/4885
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC43A1, KCNN4 KIF11 2404/4885PARP14 1958/4885GABRP 3679/4885
US-10505119-B2 Organic electroluminescence device AHR, ARNT, NAT1 KIF11 1904/4885PARP14 1305/4885GABRP 4696/4885
US-20180362843-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLCO2A1, SLCO2B1, SLCO1B3 KIF11 653/4885PARP14 2393/4885GABRP 4574/4885
US-20180212153-A1 ORGANIC ELECTROLUMINESCENCE DEVICE TYR, SLC18A1, SLC18A3 KIF11 770/4885PARP14 2542/4885GABRP 3126/4885
US-10424742-B2 Organic electroluminescent device AHR, SLC43A1, KCNN4 KIF11 2404/4885PARP14 1958/4885GABRP 3679/4885
US-11217754-B2 Organic electroluminescence device TYR, SLC18A1, SLC18A3 KIF11 770/4885PARP14 2542/4885GABRP 3126/4885
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 KIF11 3347/4885PARP14 2720/4885GABRP 4556/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 KIF11 3347/4885PARP14 2720/4885GABRP 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.