Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LCAT | P04180 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346553 | 1.00 | GRM2 (0.47) | GRM2FAAHCYP2C9CYP2C19LCAT | |
| Hydrochloric Acid SCHEMBL20582536 | 0.99 | GRM2 (0.47) | GRM2FAAHCYP2C9CYP2C19LCAT | |
| SCHEMBL19514033 | 0.90 | GRM2 (0.46) | GRM2FAAHCYP2C9CYP2C19LCAT | |
| SCHEMBL16447362 | 0.88 | FAAH (0.53) | GRM2FAAHCYP2C9CYP2C19CHRM4 | |
| SCHEMBL17878026 | 0.86 | ALDH1A1 (0.48) | CYP2C9CHRM4KCNH2ALDH1A1TSHR | |
| SCHEMBL19514120 | 0.85 | FAAH (0.47) | GRM2FAAHCYP2C9CYP2C19LCAT | |
| SCHEMBL19538687 | 0.85 | KCNH2 (0.55) | FAAHCHRM4CHRM2KCNH2EPHX2 | |
| Hydrochloric Acid SCHEMBL19514068 | 0.84 | KCNH2 (0.54) | FAAHCHRM4CHRM2KCNH2EPHX2 | |
| SCHEMBL16447469 | 0.83 | HTR2C (0.45) | GRM2 | |
| SCHEMBL15441770 | 0.83 | CHRM4 (0.49) | GRM2FAAHCYP2C9CYP2C19LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230014173-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-19 | — | — | US | disclosed |
| US-11180472-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2021-11-23 | — | — | US | disclosed |
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-01-14 | — | — | US | disclosed |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2020-07-30 | — | — | US | disclosed |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2019-10-31 | — | — | US | disclosed |
| WO-2019175737-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019175737-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-09-19 | — | — | WO | disclosed |
| US-10364232-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2019-07-30 | — | — | US | disclosed |
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
| US-20170313697-A1 | PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AND USE THEREOF | GUANGDONG GOOD MEDICINE AND HEALTH TECHNOLOGY CO., LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170313697-A1 | PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AND USE THEREOF | GUANGDONG GOOD MEDICINE AND HEALTH TECHNOLOGY CO., LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2017-06-15 | — | — | US | disclosed |
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180472-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-20170313697-A1 | PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AND USE THEREOF | ABCG2, ABCC1, PNPO | GRM2 3486/4885FAAH 4730/4885CYP2C9 29/4885 |
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | SDHA, PDF, IDH2 | GRM2 4256/4885FAAH 2500/4885CYP2C9 3230/4885 |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-10364232-B2 | Antibacterial compounds | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-20230014173-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-20200239434-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | GRM2 4810/4885FAAH 4484/4885CYP2C9 1874/4885 |
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | ALOX5, ALOX15, ALOX12 | GRM2 1460/4885FAAH 622/4885CYP2C9 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.