Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1766196 | 0.78 | KDM4E (0.32) | KDM4E | |
| SCHEMBL10694560 | 0.77 | KDM4E (0.35) | KDM4E | |
| SCHEMBL94667 | 0.76 | KDM4E (0.43) | TSHRALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL5722441 | 0.74 | KDM4E (0.41) | TSHRALDH1A1KDM4E | |
| SCHEMBL3628355 | 0.72 | NAAA (0.46) | NPSR1 | |
| SCHEMBL253364 | 0.71 | TSHR (0.43) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL2053578 | 0.70 | TSHR (0.43) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL2780857 | 0.70 | TSHR (0.40) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL15732714 | 0.70 | TSHR (0.42) | TSHRMAPTCACNA1BAPBA1CYP3A4 | |
| SCHEMBL1162364 | 0.70 | TSHR (0.42) | TSHRMAPTCACNA1BAPBA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2664665-B1 | Ophthalmic compositions with biguanide and PEG-glycerol esters | BAUSCH & LOMB (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2948196-B1 | POLY(NITROGEN/AMINE) DERIVATIVES OF A NATURAL WAX OR AN ALKOXYLATED DERIVATIVE THEREOF AND OPHTHALMIC COMPOSITIONS | BAUSCH & LOMB (US) | 2017-08-23 | — | — | EP | disclosed |
| EP-2816996-B1 | OPHTHALMIC COMPOSITIONS WITH ALKOXYLATED NATURAL WAXES | BAUSCH & LOMB (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9435073-B2 | Electrochemical textile-washing process | BASF SE (DE) | 2016-09-06 | — | — | US | disclosed |
| US-9375401-B2 | Ophthalmic compositions with alkoxylated natural waxes | Bausch ÷ Lomb Incorporated (US) | 2016-06-28 | — | — | US | disclosed |
| US-9279095-B2 | Poly(nitrogen/amine) derivatives of a natural wax and ophthalmic compositions | BAUSCH & LOMB INCORPORATED (US) | 2016-03-08 | — | — | US | disclosed |
| EP-2948196-A1 | POLY(NITROGEN/AMINE) DERIVATIVES OF A NATURAL WAX AND OPHTHALMIC COMPOSITIONS | Bausch & Lomb Incorporated (US) | 2015-12-02 | — | — | EP | disclosed |
| US-20150297511-A1 | OPHTHALMIC COMPOSITIONS WITH ALKOXYLATED NATURAL WAXES | SALIX PHARMACEUTICALS, LTD. | 2015-10-22 | — | — | US | disclosed |
| US-9125405-B2 | Contact lens solution with a tertiary amine oxide | BAUSCH & LOMB INCORPORATED (US) | 2015-09-08 | — | — | US | disclosed |
| US-9096819-B2 | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer | BAUSCH & LOMB INCORPORATED (US) | 2015-08-04 | — | — | US | disclosed |
| US-20090196845-A1 | OPTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND AN ANIONIC BIOPOLYMER | SALIX PHARMACEUTICALS, LTD. | 2009-08-06 | — | — | US | disclosed |
| US-20090196846-A1 | OPHTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND HYALURONIC ACID | BAUSCH HEALTH AMERICAS, INC. | 2009-08-06 | — | — | US | disclosed |
| WO-2009097028-A1 | OPHTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND HYALURONIC ACID | BAUSCH & LOMB INCORPORATED (US) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009032433-A1 | OPHTHALMIC COMPOSITIONS COMPRISING A CARBOXYL-MODIFIED FRUCTAN OR A SALT THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2009-03-12 | — | — | WO | disclosed |
| US-20090036404-A1 | OPHTHALMIC COMPOSITIONS COMPRISING A CARBOXYL-MODIFIED FRUCTAN OR A SALT THEREOF | ISTA PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
| US-20080311070-A1 | OPHTHALMIC COMPOSITION WITH HYALURONIC ACID | BAUSCH & LOMB INCORPORATED | 2008-12-18 | — | — | US | disclosed |
| US-20080312182-A1 | OPHTHALMIC COMPOSITION WITH HYALURONIC ACID AND POLYMERIC BIGUANIDE | BAUSCH HEALTH US, LLC | 2008-12-18 | — | — | US | disclosed |
| US-20080167215-A1 | Esterified Alkylalkoxylates Used as Low-Foam Surfactants | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-10 | — | — | US | disclosed |
| US-7074749-B2 | Oxoalcohol-based detergent | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20040009889-A1 | Detergents and cleaners comprising nonionic and/or cationic surfactants based on oxo alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312182-A1 | OPHTHALMIC COMPOSITION WITH HYALURONIC ACID AND POLYMERIC BIGUANIDE | PDE6C, PDE6H, CD44 | TSHR 1440/4885MAPT 2979/4885CACNA1B 3041/4885 |
| US-20080311070-A1 | OPHTHALMIC COMPOSITION WITH HYALURONIC ACID | UACA, GLMN, HBG1 | TSHR 919/4885MAPT 3486/4885CACNA1B 1310/4885 |
| US-20080167215-A1 | Esterified Alkylalkoxylates Used as Low-Foam Surfactants | MGLL, MSR1, LIPA | TSHR 1471/4885MAPT 4696/4885CACNA1B 4057/4885 |
| US-20090196845-A1 | OPTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND AN ANIONIC BIOPOLYMER | H1-0, H1-2, H1-3 | TSHR 289/4885MAPT 4618/4885CACNA1B 2521/4885 |
| US-20090196846-A1 | OPHTHALMIC COMPOSITIONS WITH AN AMPHOTERIC SURFACTANT AND HYALURONIC ACID | H1-0, H1-2, H1-3 | TSHR 261/4885MAPT 4785/4885CACNA1B 2720/4885 |
| US-20090036404-A1 | OPHTHALMIC COMPOSITIONS COMPRISING A CARBOXYL-MODIFIED FRUCTAN OR A SALT THEREOF | CRYZ, ACMSD, UACA | TSHR 3630/4885MAPT 1264/4885CACNA1B 1815/4885 |
| US-20150297511-A1 | OPHTHALMIC COMPOSITIONS WITH ALKOXYLATED NATURAL WAXES | ALOX15B, ALOX5, DAGLB | TSHR 3556/4885MAPT 4301/4885CACNA1B 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.