SCHEMBL17626009

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1916309	0.79	KMT2A (0.47)	ALDH1A1TDP1METAP2MEN1KMT2A
	SCHEMBL468044	0.79	RAB9A (0.41)	ALDH1A1METAP2MEN1KMT2AMAPT
	SCHEMBL5540279	0.79	RAB9A (0.47)	ALDH1A1CYP3A4TP53MEN1KMT2A
	SCHEMBL10515566	0.79	LTA4H (0.46)	ALDH1A1TP53TDP1ATP4AATP4B
	SCHEMBL500232	0.79	RAB9A (0.46)	ALDH1A1ATP4AATP4BMEN1KMT2A
	SCHEMBL971162	0.79	RAB9A (0.39)	TP53MEN1KMT2AMAPTHPGD
	SCHEMBL70645	0.78	ALDH1A1 (0.42)	ALDH1A1CYP3A4TP53MEN1KMT2A
	SCHEMBL443517	0.78	LMNA (0.43)	CYP3A4TP53KMT2AMAPTRAB9A
	SCHEMBL4711911	0.77	RECQL (0.50)	ALDH1A1CYP3A4TP53METAP2MEN1
	SCHEMBL468050	0.76	KIF11 (0.50)	ALDH1A1MEN1KMT2AKDM4EALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.