Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.36 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.34 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.34 |
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145477 | 0.78 | TSHR (0.56) | TSHRCA1CA2CA9CA7 | |
| Sulfuric Acid SCHEMBL11103729 | 0.76 | TSHR (0.68) | TSHRCA1CA2CA9CA4 | |
| SCHEMBL27704826 | 0.75 | TSHR (0.47) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL14394524 | 0.69 | TSHR (0.62) | TSHRCA1CA2CA9ALDH1A1 | |
| SCHEMBL7771649 | 0.69 | GABRA1 (0.43) | TSHRCA1CA2 | |
| SCHEMBL28301231 | 0.68 | TSHR (0.83) | TSHRCA1CA2CA9CA7 | |
| SCHEMBL28599647 | 0.68 | ESR1 (0.42) | TSHRCA1CA2CA9ACHE | |
| SCHEMBL28776948 | 0.67 | TSHR (0.65) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL29109741 | 0.67 | TSHR (0.48) | TSHRCA1CA2CA9CA4 | |
| Sulfuric Acid SCHEMBL21681660 | 0.66 | TSHR (0.71) | TSHRCA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968190-B2 | Processes for preparing oxathiazin-like compounds | GEISTLICH PHARMA AG (CH) | 2021-04-06 | — | — | US | claimed |
| EP-3233813-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | Geistlich Pharma AG (CH) | 2017-10-25 | — | — | EP | claimed |
| WO-2016098054-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2016-06-23 | — | — | WO | claimed |
| US-11999709-B2 | Processes for preparing oxathiazin-like compounds | GEISTLICH PHARMA AG (CH) | 2024-06-04 | — | — | US | disclosed |
| US-20230159477-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2023-05-25 | — | — | US | disclosed |
| US-11591302-B2 | Processes for preparing oxathiazin-like compounds | GEISTLICH PHARM A AG (CH) | 2023-02-28 | — | — | US | disclosed |
| EP-4011871-A2 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | Geistlich Pharma AG (CH) | 2022-06-15 | — | — | EP | disclosed |
| US-20210163432-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2021-06-03 | — | — | US | disclosed |
| US-10968190-B2 | Processes for preparing oxathiazin-like compounds | GEISTLICH PHARMA AG (CH) | 2021-04-06 | — | — | US | disclosed |
| US-10392355-B2 | Processes for preparing oxathiazin-like compounds | GEISTLICH PHARMA AG (CH) | 2019-08-27 | — | — | US | disclosed |
| US-20180370932-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2018-12-27 | — | — | US | disclosed |
| EP-3233813-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | Geistlich Pharma AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098054-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591302-B2 | Processes for preparing oxathiazin-like compounds | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
| US-20180370932-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
| US-20230159477-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
| US-10392355-B2 | Processes for preparing oxathiazin-like compounds | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
| US-10968190-B2 | Processes for preparing oxathiazin-like compounds | DCXR, SORD, ADH1C | CA1 2737/4885CA2 2448/4885CA4 3039/4885 |
| US-11999709-B2 | Processes for preparing oxathiazin-like compounds | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
| US-20210163432-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | OXA1L, MAPT, OTC | CA1 4841/4885CA2 4761/4885CA4 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.