Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642368 | 1.00 | KDM4E (0.58) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL31252767 | 0.85 | KDM4E (0.64) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL8242914 | 0.85 | KDM4E (0.64) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL30073106 | 0.84 | KDM4E (0.72) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL30073110 | 0.84 | KDM4E (0.72) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9595388 | 0.83 | KDM4E (0.57) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9383418 | 0.83 | KDM4E (0.57) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9383413 | 0.83 | KDM4E (0.57) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL22291829 | 0.82 | KDM4E (0.60) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL29531631 | 0.82 | KDM4E (0.60) | KDM4EALOX15TSHRSIRT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
| US-11814367-B2 | Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof | MAZE THERAPEUTICS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11739059-B2 | Oxygen scavenging molecules, articles containing same, and methods of their use | PLASTIPAK PACKAGING, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-11739059-B2 | Oxygen scavenging molecules, articles containing same, and methods of their use | PLASTIPAK PACKAGING, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2023156453-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156450-A1 | THERAPEUTIC PHENETHYLAMINE COMPOSITIONS AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2023-08-24 | — | — | WO | disclosed |
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20210403423-A1 | OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE | WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT | 2021-12-30 | — | — | US | disclosed |
| US-20210139458-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | ARVINAS OPERATIONS, INC. | 2021-05-13 | — | — | US | disclosed |
| US-20080317712-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-12-25 | — | — | US | disclosed |
| US-20080277622-A1 | Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use | WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT | 2008-11-13 | — | — | US | disclosed |
| US-20080279821-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-13 | — | — | US | disclosed |
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080234268-A1 | Bis-aryl amide derivatives and methods of use | AMGEN INC. (US) | 2008-09-25 | — | — | US | disclosed |
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| WO-2008054749-A1 | 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-7279468-B2 | Integrin ligands | ABBOTT GMBH & CO. KG (DE) | 2007-10-09 | — | — | US | disclosed |
| CN-1741995-A | Isoindoline derivative | MARUISHI PHARMA (JP) | 2006-03-01 | — | — | CN | disclosed |
| US-4030932-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814367-B2 | Inhibitors of glycogen synthase 1 (GYS1) and methods of use thereof | GYS2, GYS1, PYGL | KDM4E 2617/4885ALOX15 3328/4885TSHR 3766/4885 |
| US-20210139458-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | MDM2, CRBN, VHL | KDM4E 1438/4885ALOX15 3863/4885TSHR 2675/4885 |
| US-20080279821-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, CTSC, SPINT2 | KDM4E 1120/4885ALOX15 2864/4885TSHR 4065/4885 |
| US-20080277622-A1 | Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use | SCO2, SQOR, DUOX2 | KDM4E 1691/4885ALOX15 532/4885TSHR 3882/4885 |
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | KDM4E 3888/4885ALOX15 267/4885TSHR 4795/4885 |
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | KDM4E 4341/4885ALOX15 4002/4885TSHR 315/4885 |
| US-20080317712-A1 | ARYLPIPERIDINYL AND ARYLPYRROLIDINYL TRIPEPTIDE HEPATITIS C SERINE PROTEASE INHIBITORS | PREP, DNPEP, CTSC | KDM4E 1403/4885ALOX15 3242/4885TSHR 3955/4885 |
| US-11739059-B2 | Oxygen scavenging molecules, articles containing same, and methods of their use | SQOR, SCO2, DUOX2 | KDM4E 1731/4885ALOX15 627/4885TSHR 3883/4885 |
| US-20210403423-A1 | OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE | SQOR, SCO2, DUOX2 | KDM4E 1731/4885ALOX15 627/4885TSHR 3883/4885 |
| US-20080234268-A1 | Bis-aryl amide derivatives and methods of use | MET, REL, NAT1 | KDM4E 1448/4885ALOX15 1670/4885TSHR 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.