SCHEMBL17934962

SCHEMBL17934962

N#Cc1cc(C#N)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PTGER4 P35408 1/20 0.41
TSHR P16473 1/20 0.38
IMPDH2 P12268 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
GPR3 P46089 1/20 0.35
USP14 P54578 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
EGFR P00533 1/20 0.35
SRC P12931 1/20 0.35
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
ENPP3 O14638 1/20 0.35
RORC P51449 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968749 1.00 KDM4E (0.52) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL8282719 0.96 KDM4E (0.52) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL30570321 0.96 KDM4E (0.52) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL30968746 0.96 KDM4E (0.52) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL18381830 0.94 KDM4E (0.50) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL8739983 0.92 KDM4E (0.44) KDM4EATML3MBTL1PTGER4IMPDH2
SCHEMBL18574642 0.91 KDM4E (0.47) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL17772264 0.90 KDM4E (0.43) KDM4EATML3MBTL1PTGER4ENPP3
SCHEMBL19353833 0.90 L3MBTL1 (0.56) KDM4EATML3MBTL1PTGER4TSHR
SCHEMBL15945858 0.90 KDM4E (0.46) KDM4EATML3MBTL1PTGER4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20230354707-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-20230354707-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-20230200219-A1 A compound, an organic electroluminescent device and a display device BEIJING ETERNAL MATERIAL TECHNOLOGY CO., LTD (CN) 2023-06-22 US disclosed
US-20220158095-A1 Compound, Organic Electroluminescent Device Containing Same and Application Thereof BEIJING ETERNAL MAT TECH CO LTD (CN) 2022-05-19 US disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
US-20210351364-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE SK MATERIALS JNC CO., LTD. (KR) 2021-11-11 US disclosed
EP-3879592-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd. (JP) 2021-09-15 EP disclosed
WO-2021121230-A1 COMPOUND, APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME 北京鼎材科技有限公司 2021-06-24 WO disclosed
US-20210119169-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-04-22 US disclosed
US-20200365812-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-11-19 US disclosed
WO-2020040298-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, LUMINESCENT LAYER FORMING COMPOSITION, AND COMPOUND 学校法人関西学院 2020-02-27 WO disclosed
US-20160211466-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885ATM 3272/4885L3MBTL1 1119/4885
US-20230354707-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME ALDH1A2, L1CAM, OR10J3 KDM4E 2362/4885ATM 1922/4885L3MBTL1 21/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR KDM4E 583/4885ATM 3789/4885L3MBTL1 2263/4885
US-20220158095-A1 Compound, Organic Electroluminescent Device Containing Same and Application Thereof OR10J3, PIEZO1, TRPM8 KDM4E 1462/4885ATM 2731/4885L3MBTL1 3184/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885ATM 3272/4885L3MBTL1 1119/4885
US-20230200219-A1 A compound, an organic electroluminescent device and a display device L1CAM, VDAC2, CD274 KDM4E 2587/4885ATM 1474/4885L3MBTL1 1835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.