SCHEMBL8739983

SCHEMBL8739983

N#Cc1cc(C#N)cc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PTGER4 P35408 1/20 0.37
RORC P51449 8/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
USP14 P54578 1/20 0.34
ENPP3 O14638 1/20 0.34
IMPDH2 P12268 1/20 0.33
RPS6KB1 P23443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968749 0.92 KDM4E (0.52) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL17934962 0.92 KDM4E (0.52) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL17935128 0.90 KDM4E (0.47) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL17772264 0.89 KDM4E (0.43) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL10330893 0.89 KDM4E (0.47) KDM4EATML3MBTL1RORCALDH1A1
SCHEMBL22153415 0.89 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL22153423 0.89 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL22153422 0.89 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL18347415 0.89 KDM4E (0.50) KDM4EATML3MBTL1PTGER4RORC
SCHEMBL8739919 0.89 KDM4E (0.50) KDM4EATML3MBTL1PTGER4RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element UDC IRELAND LIMITED (IE) 2023-01-24 US disclosed
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element UDC IRELAND LIMITED (IE) 2022-10-20 US disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
US-20210351364-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE SK MATERIALS JNC CO., LTD. (KR) 2021-11-11 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
WO-2020040298-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, LUMINESCENT LAYER FORMING COMPOSITION, AND COMPOUND 学校法人関西学院 2020-02-27 WO disclosed
US-20190259955-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT-EMITTING MATERIAL THEREFOR, LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE UDC IRELAND LTD (IE) 2019-08-22 US disclosed
US-8426042-B2 Material for organic electroluminescence device, and organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-23 US disclosed
US-8420234-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2013-04-16 US disclosed
US-8415032-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2013-04-09 US disclosed
US-20120181528-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-07-19 US disclosed
US-20120153273-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885ATM 3234/4885L3MBTL1 963/4885
US-20120153273-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, AP1M1, AP2M1 KDM4E 4448/4885ATM 3217/4885L3MBTL1 94/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885ATM 3272/4885L3MBTL1 1119/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR KDM4E 583/4885ATM 3789/4885L3MBTL1 2263/4885
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC26A3, SLC43A3, SLCO2A1 KDM4E 4092/4885ATM 3592/4885L3MBTL1 1106/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KDM4E 1349/4885ATM 3192/4885L3MBTL1 212/4885
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element L1CAM, NR2E3, OR10J3 KDM4E 863/4885ATM 2619/4885L3MBTL1 156/4885
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element L1CAM, RER1, H1-0 KDM4E 3994/4885ATM 3975/4885L3MBTL1 518/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 KDM4E 4253/4885ATM 3272/4885L3MBTL1 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.