SCHEMBL18044206

SCHEMBL18044206

COc1ccccc1-c1ccc(N=Nc2cc(S(=O)(=O)O)c3ccccc3c2N)cn1

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SUMO2 P61956 1/20 0.58
▸ SUMO1 P63165 1/20 0.58
▸ SENP7 Q9BQF6 1/20 0.58
▸ SENP2 Q9HC62 1/20 0.58
▸ SENP1 Q9P0U3 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697057 1.00 SUMO2 (0.58) SUMO2SUMO1SENP7SENP2SENP1
SCHEMBL15120163 1.00 SUMO2 (0.58) SUMO2SUMO1SENP7SENP2SENP1
SCHEMBL14988339 0.99 SUMO2 (0.57) SUMO2SUMO1SENP7SENP2SENP1
SCHEMBL14988342 0.99 SUMO2 (0.57) SUMO2SUMO1SENP7SENP2SENP1
SCHEMBL18044302 0.90 — —
SCHEMBL29697134 0.90 — —
SCHEMBL15120165 0.90 — —
SCHEMBL14988341 0.90 — —
SCHEMBL14988743 0.89 — —
SCHEMBL15120187 0.89 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION KYOTO UNIVERSITY (JP) 2025-02-20 — — US claimed
EP-4454648-A1 COMPOSITION FOR IMPROVING HEART FUNCTION Kyoto University (JP) 2024-10-30 — — EP claimed
US-20240216397-A1 COMPOSITION FOR AMELIORATING SKIN TISSUE ABNORMALITY KYOTO UNIVERSITY (JP) 2024-07-04 — — US claimed
US-12011438-B2 Composition for protecting cardiomyocyte KYOTO UNIVERSITY (JP) 2024-06-18 — — US claimed
EP-4331589-A1 COMPOSITION FOR AMELIORATING ABNORMALITY OF SKIN TISSUE Kyoto University (JP) 2024-03-06 — — EP claimed
WO-2023140242-A1 COMPOSITION FOR PROTECTING TISSUE ISOLATED FROM LIVING BODY 国立大学法人京都大学 2023-07-27 — — WO claimed
WO-2023120704-A1 COMPOSITION FOR IMPROVING HEART FUNCTION 国立大学法人京都大学 2023-06-29 — — WO claimed
US-20220401461-A1 Pharmaceutical Composition for Protecting Cartilage KYOTO UNIVERSITY (JP) 2022-12-22 — — US claimed
WO-2022230949-A1 COMPOSITION FOR AMELIORATING ABNORMALITY OF SKIN TISSUE 国立大学法人京都大学 2022-11-03 — — WO claimed
EP-4049724-A1 PHARMACEUTICAL COMPOSITION FOR PROTECTING CARTILAGE Kyoto University (JP) 2022-08-31 — — EP claimed
CN-111757733-A Composition for protecting cornea 国立大学法人京都大学 2020-10-09 — — CN claimed
WO-2020027137-A1 MEDICINE COMPOSITION FOR TREATING CEREBRAL INFARCTION 国立大学法人京都大学 2020-02-06 — — WO claimed
WO-2019203176-A1 PHARMACEUTICAL COMPOSITION FOR PROTECTING MYOCARDIAL CELLS 国立大学法人京都大学 2019-10-24 — — WO claimed
EP-3042658-B1 MEDICINAL COMPOSITION IMPROVING LEPTIN RESISTANCE UNIV KYOTO (JP) 2019-01-16 — — EP claimed
EP-2959903-B1 MEDICINE FOR TREATING EYE DISEASE UNIV KYOTO (JP) 2018-10-03 — — EP claimed
US-9931351-B2 Method for improving leptin resistance KYOTO UNIVERSITY (JP) 2018-04-03 — — US claimed
US-9782420-B2 Method for treating eye diseases KYOTO UNIVERSITY (JP) 2017-10-10 — — US claimed
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 — — US claimed
US-20160303144-A1 Medicinal Composition Improving Leptin Resistance KYOTO UNIVERSITY (JP) 2016-10-20 — — US claimed
EP-2599771-B1 NAPHTHALENE DERIVATIVE DAITO CHEMIX CORP (JP) 2016-09-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION TNNI3, NPPA, TNNT2 SUMO2 4148/4885SUMO1 3183/4885SENP7 2221/4885
US-12011438-B2 Composition for protecting cardiomyocyte TNNI3, TNNT2, TNNC1 SUMO2 2295/4885SUMO1 2239/4885SENP7 2498/4885
US-20160303144-A1 Medicinal Composition Improving Leptin Resistance LIPC, ADIPOR1, GPR119 SUMO2 4540/4885SUMO1 4341/4885SENP7 2517/4885
US-20220401461-A1 Pharmaceutical Composition for Protecting Cartilage COL2A1, MATR3, COL1A1 SUMO2 2757/4885SUMO1 1171/4885SENP7 1925/4885
US-20240216397-A1 COMPOSITION FOR AMELIORATING SKIN TISSUE ABNORMALITY CUTA, FABP4, MMP13 SUMO2 3580/4885SUMO1 3459/4885SENP7 2588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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