Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944489 | 0.88 | DPP4 (0.43) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL23518518 | 0.84 | ALDH1A1 (0.42) | FAAHHPGDMEN1CYP1A2CYP3A4 | |
| SCHEMBL12335993 | 0.82 | FAAH (0.35) | FAAHPHGDHMGLLKCNQ3KCNQ2 | |
| SCHEMBL1515195 | 0.80 | MEN1 (0.47) | FAAHMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL803099 | 0.80 | MEN1 (0.52) | MEN1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL15119954 | 0.80 | ALDH1A1 (0.38) | FAAHPHGDHMGLLKCNQ3KCNQ2 | |
| SCHEMBL22030493 | 0.79 | KDM4E (0.38) | FAAHMEN1CYP2C19KMT2AALDH1A1 | |
| SCHEMBL20121992 | 0.78 | MEN1 (0.55) | MEN1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL23080297 | 0.78 | MEN1 (0.55) | MEN1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL20121989 | 0.78 | MEN1 (0.55) | MEN1CYP1A2CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190308-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130184303-A1 | PYRIDO[4,3-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8455479-B2 | Heterocyclic compounds | PANACEA BIOTEC LIMITED (IN) | 2013-06-04 | — | — | US | disclosed |
| US-8389728-B2 | Pollen tube stimulants from Arabidopsis pistils | THE ARIZONA BOARD OF REGENTS (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389728-B2 | Pollen tube stimulants from Arabidopsis pistils | THE ARIZONA BOARD OF REGENTS (US) | 2013-03-05 | — | — | US | disclosed |
| US-20110111959-A1 | POLLEN TUBE STIMULANTS FROM ARABIDOPSIS PISTILS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2011-05-12 | — | — | US | disclosed |
| US-20110111959-A1 | POLLEN TUBE STIMULANTS FROM ARABIDOPSIS PISTILS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2011-05-12 | — | — | US | disclosed |
| US-20100311732-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC PHARMA LIMITED (IN) | 2010-12-09 | — | — | US | disclosed |
| US-20090264384-A1 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF | NUADA, INC. (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090005344-A1 | Compounds and Methods of Use Thereof | NKUADA, LLC (US) | 2009-01-01 | — | — | US | disclosed |
| US-20080319044-A1 | Compounds and Methods of Use Thereof | NUADA, LLC (US) | 2008-12-25 | — | — | US | disclosed |
| EP-1216247-B1 | IMIDAZOIMIDAZOLES AND TRIAZOLES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMA (US) | 2008-11-05 | — | — | EP | disclosed |
| US-20080269204-A1 | Compounds and Methods of Use Thereof | DYAKONOV TATYANA | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005344-A1 | Compounds and Methods of Use Thereof | TNF, IL1B, TNFRSF1A | FAAH 2243/4885PHGDH 2507/4885MGLL 2944/4885 |
| US-20130190308-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | FAAH 383/4885PHGDH 703/4885MGLL 3972/4885 |
| US-20110111959-A1 | POLLEN TUBE STIMULANTS FROM ARABIDOPSIS PISTILS | MYB, GFM1, GET3 | FAAH 1180/4885PHGDH 3329/4885MGLL 1248/4885 |
| US-20130184303-A1 | PYRIDO[4,3-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | FAAH 371/4885PHGDH 669/4885MGLL 3921/4885 |
| US-20080269204-A1 | Compounds and Methods of Use Thereof | TNF, LITAF, TNFRSF1A | FAAH 1719/4885PHGDH 2584/4885MGLL 1294/4885 |
| US-20090264384-A1 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF | TNF, NFKBIA, IL6 | FAAH 1394/4885PHGDH 2183/4885MGLL 1022/4885 |
| US-20100311732-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DPP4, DPP3, DPP8 | FAAH 1848/4885PHGDH 478/4885MGLL 2876/4885 |
| US-20080319044-A1 | Compounds and Methods of Use Thereof | TNF, LITAF, LTA | FAAH 1284/4885PHGDH 2772/4885MGLL 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.