Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of (R)-3-Hydroxybutanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-3-Hydroxybutanoate SCHEMBL1331366 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL19915248 | 1.00 | CA2 (0.65) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332197 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL194589 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL7765391 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332447 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1330790 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL21060562 | 0.94 | CA2 (0.57) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321684 | 0.94 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321678 | 0.94 | CA2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4595774-A1 | COMPLEX OF 3-HYDROXYBUTYRIC ACID AND SODIUM 3-HYDROXYBUTYRATE AND PREPARATION METHOD THEREFOR | Nanjing Nutrabuilding Bio-Tech Co., Ltd. (CN) | 2025-08-06 | — | — | EP | claimed |
| US-20250221948-A1 | Complex of 3-hydroxybutyric acid and sodium 3-hydroxybutyrate and preparation method thereof | NANJING NUTRABUILDING BIO-TECH CO., LTD. (CN) | 2025-07-10 | — | — | US | claimed |
| CN-119968131-A | 3-Hydroxybutyric acid and sodium 3-hydroxybutyrate compound and preparation method thereof | 南京纽邦生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| US-12171735-B2 | Administration of butyrate, beta-hydroxybutyrate, cannabidiol, and related compounds in humans | AXCESS GLOBAL SCIENCES, LLC (US) | 2024-12-24 | — | — | US | claimed |
| US-12128020-B2 | Administration of R-beta-hydroxybutyrate and related compounds in humans | AXCESS GLOBAL SCIENCES, LLC (US) | 2024-10-29 | — | — | US | claimed |
| US-12109182-B2 | Administration of R-beta-hydroxybutyrate and related compounds in humans | AXCESS GLOBAL SCIENCES, LLC (US) | 2024-10-08 | — | — | US | claimed |
| US-20240226043-A1 | ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS | AXCESS GLOBAL SCIENCES, LLC | 2024-07-11 | — | — | US | claimed |
| WO-2024067584-A1 | COMPLEX OF 3-HYDROXYBUTYRIC ACID AND SODIUM 3-HYDROXYBUTYRATE AND PREPARATION METHOD THEREFOR | 南京纽邦生物科技有限公司 | 2024-04-04 | — | — | WO | claimed |
| CN-117503807-A | Preparation process of cordyceps militaris powder | 江西仙客来生物科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| EP-3445355-B1 | BETA-HYDROXYBUTYRATE FOR USE IN NON-THERAPEUTIC METHODS OF CONTROLLING WEIGHT LOSS AND KETOTIS | AXCESS GLOBAL SCIENCES LLC (US) | 2023-11-29 | — | — | EP | claimed |
| US-10973792-B2 | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use | AXCESS GLOBAL SCIENCES, LLC (US) | 2021-04-13 | — | — | US | claimed |
| WO-2020167690-A1 | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE | ACCESS GLOBAL SCIENCES, LLC (US) | 2020-08-20 | — | — | WO | claimed |
| US-20200253909-A1 | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE | AXCESS GLOBAL SCIENCES, LLC | 2020-08-13 | — | — | US | claimed |
| CN-110248652-A | 3-hydroxybutyrate is used singly or in combination to treatment intensive care | 鲁汶大学 | 2019-09-17 | — | — | CN | claimed |
| CN-110035991-A | One-step fermentation prepares (R) -3-hydroxybutyrate or its salt | NNB营养品美国有限公司 | 2019-07-19 | — | — | CN | claimed |
| EP-3507272-A1 | PREPARATION OF (R)-3-HYDROXYBUTYRIC ACID OR ITS SALTS BY ONE-STEP FERMENTATION | NNB Nutrition USA, LLC (US) | 2019-07-10 | — | — | EP | claimed |
| WO-2018187324-A1 | PREPARATION OF (R)-3-HYDROXYBUTYRIC ACID OR ITS SALTS BY ONE-STEP FERMENTATION | NNB Nutrition USA, LLC (US) | 2018-10-11 | — | — | WO | claimed |
| US-20180282767-A1 | PREPARATION OF (R)-3-HYDROXYBUTYRIC ACID OR ITS SALTS BY ONE-STEP FERMENTATION | NANJING NUTRABUILDING BIO-TECH CO., LTD. (CN) | 2018-10-04 | — | — | US | claimed |
| CN-107162893-A | (R) synthesis technique of 3 hydroxybutyric acids and its salt | 洛阳华荣生物技术有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-101974603-A | Method for producing D-alpha-hydroxybutyric acid | UNIV SHANDONG | 2011-02-16 | — | — | CN | claimed |