Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of (R)-3-Hydroxybutanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-3-Hydroxybutanoate SCHEMBL1819385 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1331366 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL19915248 | 1.00 | CA2 (0.65) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332197 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL194589 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332447 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1330790 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL21060562 | 0.94 | CA2 (0.57) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321684 | 0.94 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321678 | 0.94 | CA2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248652-B | 3-hydroxybutyric acid alone or in combination for intensive care therapy | 鲁汶大学 | 2023-05-26 | — | — | CN | claimed |
| EP-3923925-A1 | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE | Axcess Global Sciences, LLC (US) | 2021-12-22 | — | — | EP | claimed |
| US-20210177786-A1 | RACEMIC AND NEAR RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS | AXCESS GLOBAL SCIENCES, LLC | 2021-06-17 | — | — | US | claimed |
| US-10973792-B2 | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use | AXCESS GLOBAL SCIENCES, LLC (US) | 2021-04-13 | — | — | US | claimed |
| WO-2020167690-A1 | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE | ACCESS GLOBAL SCIENCES, LLC (US) | 2020-08-20 | — | — | WO | claimed |
| US-20200253909-A1 | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE | AXCESS GLOBAL SCIENCES, LLC | 2020-08-13 | — | — | US | claimed |
| CN-110248652-A | 3-hydroxybutyrate is used singly or in combination to treatment intensive care | 鲁汶大学 | 2019-09-17 | — | — | CN | claimed |
| US-12409159-B2 | 3-hydroxybutyrate alone or in combination for use in the treatment of critical care treatment | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-09-09 | — | — | US | disclosed |
| US-20230310353-A1 | 3-HYDROXYBUTYRATE ALONE OR IN COMBINATION FOR USE IN THE TREATMENT OF CRITICAL CARE TREATMENT | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-10-05 | — | — | US | disclosed |
| CN-110248652-B | 3-hydroxybutyric acid alone or in combination for intensive care therapy | 鲁汶大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-2914563-B1 | PRINTING PROCESS | WZR CERAM SOLUTIONS GMBH (DE) | 2021-06-30 | — | — | EP | disclosed |
| CN-110248652-A | 3-hydroxybutyrate is used singly or in combination to treatment intensive care | 鲁汶大学 | 2019-09-17 | — | — | CN | disclosed |
| EP-2914563-A1 | PRESSURE PROCESS | WZR Ceramic Solutions GmbH (DE) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014067990-A1 | PRESSURE PROCESS | WZR ceramic solutions GmbH (DE) | 2014-05-08 | — | — | WO | disclosed |
| CN-101974603-A | Method for producing D-alpha-hydroxybutyric acid | UNIV SHANDONG | 2011-02-16 | — | — | CN | disclosed |
| EP-1105416-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | Keystone Biomedical, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6063919-A | ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) | KEYSTONE BIOMEDICAL, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-2000009547-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | KEYSTONE BIOMEDICAL, INC. (US) | 2000-02-24 | — | — | WO | disclosed |