Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of (R)-3-Hydroxybutanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-3-Hydroxybutanoate SCHEMBL1819385 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1331366 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL19915248 | 1.00 | CA2 (0.65) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332197 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL7765391 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1332447 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL1330790 | 1.00 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL21060562 | 0.94 | CA2 (0.57) | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321684 | 0.94 | — | — | |
| (R)-3-Hydroxybutanoate SCHEMBL22321678 | 0.94 | CA2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 911 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260130876-A1 | ADMINISTRATION OF BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS | AXCESS GLOBAL SCIENCES LLC (US) | 2026-05-14 | — | — | US | claimed |
| US-12551455-B2 | Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate | AXCESS GLOBAL SCIENCES, LLC (US) | 2026-02-17 | — | — | US | claimed |
| US-12496283-B2 | Administration of R-beta-hydroxybutyrate and related compounds in humans | AXCESS GLOBAL SCIENCES, LLC (US) | 2025-12-16 | — | — | US | claimed |
| US-12396974-B2 | Ketone ester as a therapeutic treatment of Covid-19 and related viral infections | KetoneAid (US) | 2025-08-26 | — | — | US | claimed |
| EP-4595774-A1 | COMPLEX OF 3-HYDROXYBUTYRIC ACID AND SODIUM 3-HYDROXYBUTYRATE AND PREPARATION METHOD THEREFOR | Nanjing Nutrabuilding Bio-Tech Co., Ltd. (CN) | 2025-08-06 | — | — | EP | claimed |
| US-20250221948-A1 | Complex of 3-hydroxybutyric acid and sodium 3-hydroxybutyrate and preparation method thereof | NANJING NUTRABUILDING BIO-TECH CO., LTD. (CN) | 2025-07-10 | — | — | US | claimed |
| CN-120130645-A | Extraction method and application of agaricus bisporus fermentation product | 吉林农业大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119968131-A | 3-Hydroxybutyric acid and sodium 3-hydroxybutyrate compound and preparation method thereof | 南京纽邦生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119926968-A | Method for constructing functional bacteria ecological niche in soil to degrade chlorinated hydrocarbon in soil | 中铁四局集团第四工程有限公司 | 2025-05-06 | — | — | CN | claimed |
| WO-2025085934-A1 | MITIGATING PASSIVATION OF METAL ELECTRODES | FORM ENERGY, INC. (US) | 2025-04-24 | — | — | WO | claimed |
| WO-2007007025-A1 | CORROSION INHIBITOR OR INTENSIFIER FOR USE IN ACIDIZING TREATMENT FLUIDS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| US-20070010404-A1 | Corrosion inhibitor or intensifier for use in acidizing treatment fluids | HALLIBURTON ENERGY SERVICES, INC. | 2007-01-11 | — | — | US | claimed |
| US-6613356-B1 | Medication for weight loss by means of appetite suppression and a method for administering this medication to humans and other mammals. The medication comprises potassium butyrate or closely related chemical compounds, together with chemicals | AXCESS GLOBAL SCIENCES, LLC | 2003-09-02 | — | — | US | claimed |
| US-6562872-B1 | Rapidly eliminable perfluorocarbon (PFC) and a slowly eliminable perfluorinated cyclic tertiary amine, perfluoro-N-4- (methylcyclohexyl)-piperidine and additionally comprises not less then three rapidly eliminable and three | Otkrytoe Aktsionernoe Obschestvo Naucho-Proizvodstven-Naya Firma “Perftoran” (RU) | 2003-05-13 | — | — | US | claimed |
| EP-1306083-A1 | EMULSION OF PERFLUORORGANIC COMPOUNDS FOR MEDICAL PURPOSES, METHOD FOR PRODUCING SAID EMULSION AND METHODS FOR CURING AND PREVENTING DISEASES WITH THE AID OF THE EMULSION | Otkrytoe Aktsionernoe Obchestvo Nauchno-Proizvodstvennaya Firma "Perftoran" (RU) | 2003-05-02 | — | — | EP | claimed |
| EP-0780123-B1 | Beta-hydroxybutyric acid or acetoacetic acid or salts or esters therof for use in improving cerebral function | BTG INT LTD (GB) | 2002-06-12 | — | — | EP | claimed |
| EP-1188437-A2 | Beta-hydroxybutyric acid or acetoacetic acid or salts or esters therof for use in improving cerebral function | BTG INTERNATIONAL LIMITED (GB) | 2002-03-20 | — | — | EP | claimed |
| US-6136862-A | INTRAVENOUSLY ADMINISTERING AN ORGANIC ACID, ESTER, OR SALT THEREOF | SHIMIZU PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0355453-A2 | Use of 3-hydroxybutyric acid as an energy source | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-28 | — | — | EP | claimed |
| US-4138291-A | OBTAINING BACTERIA STRAIN WHICH CAN CONVERT CARBON SOURCE INTO POLY-(D-3-HYDROXYBUTYRIC ACID) | AGROFERM AG (CH) | 1979-02-06 | — | — | US | claimed |