Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.34 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL5819722 | 0.89 | ADRB2 (0.38) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| SCHEMBL15048640 | 0.83 | ADRB2 (0.41) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| Ether SCHEMBL4785780 | 0.83 | ALDH1A1 (0.40) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| Ether SCHEMBL2872980 | 0.82 | ALDH1A1 (0.39) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| SCHEMBL2872983 | 0.81 | ICAM1 (0.39) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| SCHEMBL15048641 | 0.75 | KDM4E (0.41) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| Ether SCHEMBL10413224 | 0.74 | ADRB2 (0.41) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| Ether SCHEMBL1678479 | 0.74 | ALDH1A1 (0.42) | ADRB2ADRB1LMNAHTR1AADRA2C | |
| 2-Allylphenol SCHEMBL1777274 | 0.74 | POLB (0.42) | ADRB2LMNAHTR1AALDH1A1KDM4E | |
| SCHEMBL10192351 | 0.73 | ALDH1A1 (0.49) | ADRB2ADRB1LMNAHTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146479-A2 | POLYMER AND POLYMER EMULSION, PREPARATION METHOD THEREFOR, CEMENT SLURRY, AND APPLICATION OF POLYMER AND POLYMER EMULSION | 中国石油化工股份有限公司 | 2024-07-11 | — | — | WO | claimed |
| CN-118185014-A | Methyl phenyl silicone resin emulsion and preparation method thereof | 浙江开化合成材料有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118166438-A | Meta-aramid pre-spinning oiling agent and preparation and use methods thereof | 江苏新视界先进功能纤维创新中心有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117757360-A | Corrosion-resistant liquid wax for large-size monocrystalline silicon wafer and preparation method thereof | 江苏奥首材料科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117534789-B | Polyacrylamide suspension emulsion for fracturing and preparation method thereof | 东营众悦石油科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117730857-A | Beta-cyclodextrin coated tebuconazole metal complex mildew inhibitor and preparation method thereof | 广东迪美生物技术有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117717084-A | Post-emergence stem leaf herbicide | 沈阳农业大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117659289-A | Oxazoline modified styrene-acrylic emulsion and preparation method thereof | 重庆市化工研究院有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117659276-A | Clay stabilizer for fracturing and acidizing and preparation method thereof | 滨州市广友石油科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117534789-A | Polyacrylamide suspension emulsion for fracturing and preparation method thereof | 东营众悦石油科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-113425022-A | Preparation method of bionic plant leaf micro-nano structure and performance of wood/bamboo-based furniture decorative material surface morphism method | 中杭监测技术研究院有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-113133464-A | Preparation method of chlorophyll photoactivation pesticide | 石启田 | 2021-07-20 | — | — | CN | claimed |
| CN-108976438-B | Thermodynamic self-emulsifying efficient emulsifier for paraffin for softening wood and preparation method thereof | 张健 | 2021-05-25 | — | — | CN | claimed |
| CN-107674767-B | Automobile three-way catalyst cleaning agent and preparation method thereof | 北京昊天鸿运化工科技有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-108620413-B | Recycling method and application of water-based asphalt paint slag | 湖南路美工程材料有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-107722299-B | Terpene resin dispersion glue and preparation method thereof | 黎月清 | 2020-09-18 | — | — | CN | claimed |
| CN-107777961-B | High-strength self-compacting concrete easy for super high-rise pumping | 北京市第五建筑工程集团有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-111269675-A | Cigarette filter tip glue and preparation method thereof | 中国烟草总公司郑州烟草研究院 | 2020-06-12 | — | — | CN | claimed |
| CN-108084967-B | Magnetizing base permeation-increasing wetting agent for improving coal seam water injection and dust reduction effects | 中国矿业大学 | 2020-05-19 | — | — | CN | claimed |
| CN-111072830-A | Preparation method of phellandrene resin emulsion | 黎月清 | 2020-04-28 | — | — | CN | claimed |