SCHEMBL1849326

SCHEMBL1849326

CCC(OC(=O)CCS)(OC(=O)CCS)OC(=O)CCS

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1854976 0.87 TSHR (0.34) ALDH1A1TSHRHSD17B10
SCHEMBL23826 0.81 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL1849070 0.81 TSHR (0.46) TSHRHSD17B10
SCHEMBL18266766 0.80 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10
SCHEMBL10335513 0.80 ALDH1A1 (0.31) ALDH1A1TSHRHSD17B10
SCHEMBL25887012 0.80 TSHR (0.34) ALDH1A1TSHRHSD17B10
SCHEMBL12533512 0.78 ALDH1A1 (0.30) ALDH1A1TSHRHSD17B10
SCHEMBL3899462 0.76 HDAC6 (0.37) TSHRHSD17B10ACE
SCHEMBL1988721 0.74 TSHR (0.42) ALDH1A1TSHRHSD17B10
SCHEMBL10501119 0.74 HDAC6 (0.36) TSHRHSD17B10ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700576-A ACRYLATED ESTER POLYMERS ROEHM GMBH CHEMISCHE FABRIK (DE) 1997-12-23 US claimed
US-20230211011-A1 TARGETED CRYSTALLIZATION OF MIXED-CHARGE NANOPARTICLES IN LYSOSOMES FOR INDUCING SELECTIVE DEATH OF CANCER CELLS INSTITUTE FOR BASIC SCIENCE (KR) 2023-07-06 US disclosed
US-8252296-B2 Aqueous polymer dispersion and use thereof in cosmetics BASF SE (DE) 2012-08-28 US disclosed
US-8247507-B2 Cationic polymers as thickeners for aqueous and alcoholic compositions BASF SE (DE) 2012-08-21 US disclosed
US-8173583-B2 Use of cationic copolymers of amine-containing acrylates and N-vinylimidazolium salts in hair cosmetic preparations BASF SE (DE) 2012-05-08 US disclosed
EP-2066705-B1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS BASF SE (DE) 2011-05-25 EP disclosed
EP-2114365-B1 CATIONIC CONDITIONING AGENT BASF SE (DE) 2010-09-01 EP disclosed
US-20100204045-A1 Systemicity Enhancers BASF SE (DE) 2010-08-12 US disclosed
US-20100179082-A1 USE OF CATIONIC COPOLYMERS OF AMINE-CONTAINING ACRYLATES AND N-VINYLIMIDAZOLIUM SALTS IN HAIR COSMETIC PREPARATIONS BASF SE (DE) 2010-07-15 US disclosed
US-20100119468-A1 CATIONIC CONDITIONING AGENT BASF SE (DE) 2010-05-13 US disclosed
US-20080139690-A1 Coating Agents for Producing Formable, Scratch and Soiling-Resistant Coatings, Scratch-Resistant, Formable and Soiling-Resistant Shaped Bodies and a Method for the Production Thereof ROEHM GMBH (DE) 2008-06-12 US disclosed
US-20070197767-A1 Method for producing polymers that are predominantly formed from vinvyl formamide BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US disclosed
EP-1646663-B1 AQUEOUS POLYMER DISPERSION AND USE THEREOF IN COSMETICS BASF AG (DE) 2007-01-24 EP disclosed
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 US disclosed
US-20060122322-A1 Aqueous polymer dispersions BASF AKTIENGESELLSCHAFT (DE) 2006-06-08 US disclosed
US-20060058458-A1 Coating agents for producing rigid coatings resistant to scratching and soiling and rigid moulded bodies resistant to scratching and soiling and method for the production thereof ROEHM GMBH & CO. KG (DE) 2006-03-16 US disclosed
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair BASF AKTIENGESELLSCHAFT (DE) 2005-12-01 US disclosed
EP-0730011-B1 Scratch-resistant, UV-curable coating containing a copolymerizable thickener ROEHM GMBH (DE) 1998-12-09 EP disclosed
US-5700576-A ACRYLATED ESTER POLYMERS ROEHM GMBH CHEMISCHE FABRIK (DE) 1997-12-23 US disclosed
EP-0730011-A1 Scratch-resistant, UV-curable coating containing a copolymerizable thickener RÖHM GMBH (DE) 1996-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics ALAD, ACMSD, PADI4 ALDH1A1 291/4885TSHR 4155/4885HSD17B10 153/4885
US-20100179082-A1 USE OF CATIONIC COPOLYMERS OF AMINE-CONTAINING ACRYLATES AND N-VINYLIMIDAZOLIUM SALTS IN HAIR COSMETIC PREPARATIONS ASS1, ACR, PADI1 ALDH1A1 187/4885TSHR 3874/4885HSD17B10 1569/4885
US-20100204045-A1 Systemicity Enhancers C3AR1, C5, CHRM1 ALDH1A1 1609/4885TSHR 1208/4885HSD17B10 2527/4885
US-20100119468-A1 CATIONIC CONDITIONING AGENT HLA-DRB1, CD47, CD74 ALDH1A1 2666/4885TSHR 3616/4885HSD17B10 4378/4885
US-20230211011-A1 TARGETED CRYSTALLIZATION OF MIXED-CHARGE NANOPARTICLES IN LYSOSOMES FOR INDUCING SELECTIVE DEATH OF CANCER CELLS CTSA, CTSS, LAMP1 ALDH1A1 4377/4885TSHR 3875/4885HSD17B10 4080/4885
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair ETF1, MTHFD2, TWF2 ALDH1A1 2687/4885TSHR 2185/4885HSD17B10 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.