SCHEMBL1854976

SCHEMBL1854976

CCC(OC(=O)CCCS)(OC(=O)CCCS)OC(=O)CCCS

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.34
FOLH1 Q04609 1/20 0.33
DGKA P23743 1/20 0.32
CYP1A2 P05177 1/20 0.32
DNM1 Q05193 1/20 0.31
LMNA P02545 3/20 0.31
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1849326 0.87 ALDH1A1 (0.32) TSHRALDH1A1HSD17B10
SCHEMBL5720661 0.84
SCHEMBL18266763 0.82 TSHR (0.33) TSHRFOLH1DGKACYP1A2DNM1
SCHEMBL16415782 0.79 DGKA (0.55) TSHRDGKALMNAKDM4EDUSP3
SCHEMBL16416009 0.79 DGKA (0.55) TSHRDGKALMNAKDM4EDUSP3
SCHEMBL6738496 0.78 EPHX2 (0.39) TSHRFOLH1MEN1KMT2AHSD17B10
SCHEMBL1849070 0.78 TSHR (0.46) TSHRHSD17B10
SCHEMBL23826 0.78 ALDH1A1 (0.52) TSHRDGKALMNAALDH1A1
SCHEMBL10610161 0.77 TSHR (0.41) TSHRDGKACYP1A2LMNAKDM4E
SCHEMBL10612910 0.75 DGKA (0.36) TSHRDGKACYP1A2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252296-B2 Aqueous polymer dispersion and use thereof in cosmetics BASF SE (DE) 2012-08-28 US disclosed
US-8247507-B2 Cationic polymers as thickeners for aqueous and alcoholic compositions BASF SE (DE) 2012-08-21 US disclosed
US-8173583-B2 Use of cationic copolymers of amine-containing acrylates and N-vinylimidazolium salts in hair cosmetic preparations BASF SE (DE) 2012-05-08 US disclosed
EP-2066705-B1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS BASF SE (DE) 2011-05-25 EP disclosed
EP-2114365-B1 CATIONIC CONDITIONING AGENT BASF SE (DE) 2010-09-01 EP disclosed
US-20100204045-A1 Systemicity Enhancers BASF SE (DE) 2010-08-12 US disclosed
US-20100179082-A1 USE OF CATIONIC COPOLYMERS OF AMINE-CONTAINING ACRYLATES AND N-VINYLIMIDAZOLIUM SALTS IN HAIR COSMETIC PREPARATIONS BASF SE (DE) 2010-07-15 US disclosed
US-20100119468-A1 CATIONIC CONDITIONING AGENT BASF SE (DE) 2010-05-13 US disclosed
US-20100040573-A1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS BASF SE (DE) 2010-02-18 US disclosed
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080153925-A1 Use of Amphiphilic Copolymers as Solubilising Agents BASF AKTIENGESELLSCHAFT (DE) 2008-06-26 US disclosed
EP-1863858-A1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2007-12-12 EP disclosed
US-20070197767-A1 Method for producing polymers that are predominantly formed from vinvyl formamide BASF AKTIENGESELLSCHAFT (DE) 2007-08-23 US disclosed
EP-1781719-A1 USE OF AMPHIPHILIC COPOLYMERS AS SOLUBILISING AGENTS BASF Aktiengesellschaft (DE) 2007-05-09 EP disclosed
EP-1646663-B1 AQUEOUS POLYMER DISPERSION AND USE THEREOF IN COSMETICS BASF AG (DE) 2007-01-24 EP disclosed
WO-2006097514-A1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 WO disclosed
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 US disclosed
WO-2006018135-A1 USE OF AMPHIPHILIC COPOLYMERS AS SOLUBILISING AGENTS BASF AKTIENGESELLSCHAFT (DE) 2006-02-23 WO disclosed
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair BASF AKTIENGESELLSCHAFT (DE) 2005-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194708-A1 Cationic Polymers as Thickeners for Aqueous and Alcoholic Compositions ADH1A, ADH1C, PCNA TSHR 4389/4885FOLH1 2682/4885DGKA 114/4885
US-20060153793-A1 Aqueous polymer dispersion and use thereof in cosmetics ALAD, ACMSD, PADI4 TSHR 4155/4885FOLH1 4006/4885DGKA 1317/4885
US-20100179082-A1 USE OF CATIONIC COPOLYMERS OF AMINE-CONTAINING ACRYLATES AND N-VINYLIMIDAZOLIUM SALTS IN HAIR COSMETIC PREPARATIONS ASS1, ACR, PADI1 TSHR 3874/4885FOLH1 2625/4885DGKA 3949/4885
US-20100040573-A1 CATIONIC POLYMERS AS THICKENERS FOR AQUEOUS AND ALCOHOLIC COMPOSITIONS ADH1A, ADH1C, ARCN1 TSHR 4536/4885FOLH1 2381/4885DGKA 117/4885
US-20080153925-A1 Use of Amphiphilic Copolymers as Solubilising Agents VCL, ASS1, CCNL2 TSHR 4319/4885FOLH1 4541/4885DGKA 1797/4885
US-20100204045-A1 Systemicity Enhancers C3AR1, C5, CHRM1 TSHR 1208/4885FOLH1 2856/4885DGKA 936/4885
US-20100119468-A1 CATIONIC CONDITIONING AGENT HLA-DRB1, CD47, CD74 TSHR 3616/4885FOLH1 2504/4885DGKA 1760/4885
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair ETF1, MTHFD2, TWF2 TSHR 2185/4885FOLH1 938/4885DGKA 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.