SCHEMBL18566635

SCHEMBL18566635

O=C(O)c1cc(Br)c2ccccc2c1-c1cccc2c1oc1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.47
▸ PRNP P04156 1/20 0.40
▸ HDAC8 Q9BY41 1/20 0.40
▸ GGPS1 O95749 1/20 0.40
▸ PRKDC P78527 3/20 0.39
▸ TBK1 Q9UHD2 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.38
▸ USP2 O75604 1/20 0.38
▸ CSNK2A2 P19784 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ CSNK2B P67870 1/20 0.38
▸ CSNK2A1 P68400 1/20 0.38
▸ CSNK2A3 Q8NEV1 1/20 0.38
▸ GPR35 Q9HC97 1/20 0.38
▸ TTR P02766 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18566634 0.85 HDAC8 (0.47) ALOX5HDAC8KDM4EHTTKMT2A
SCHEMBL21510861 0.84 KDM4E (0.49) ALOX5HDAC8GGPS1PRKDCTBK1
SCHEMBL17917528 0.81 ALOX5 (0.48) ALOX5HDAC8GGPS1PRKDCTBK1
SCHEMBL18165289 0.80 ALOX5 (0.55) ALOX5HDAC8GGPS1PRKDCTBK1
SCHEMBL18854814 0.79 ALOX5 (0.55) ALOX5HDAC8GGPS1PRKDCKDM4E
SCHEMBL22054377 0.78 WDR5 (0.59) ALOX5KDM4EGPR35MEN1HTT
SCHEMBL19774396 0.78 PRMT1 (0.35) PRNPGPR35MEN1THRBHTT
SCHEMBL18566653 0.78 ALOX5 (0.43) ALOX5HDAC8GGPS1PRKDCMEN1
SCHEMBL18364038 0.77 ALOX5 (0.45) ALOX5HDAC8GGPS1PRKDCTBK1
SCHEMBL9890833 0.76 ALOX5 (0.57) ALOX5GGPS1PRKDCKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 — — US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 — — US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 — — US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 — — US disclosed
US-11563181-B2 Amine compounds for organic light-emitting diode and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-01-24 — — US disclosed
EP-4116297-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC Co., Ltd. (KR) 2023-01-11 — — EP disclosed
US-11532792-B2 Organic light emitting diode having high efficiency SFC CO., LTD. (KR) 2022-12-20 — — US disclosed
EP-3144302-B1 HETEROCYCLIC COMPOUND CONTAINING AROMATIC AMINE GROUP, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO LTD (KR) 2021-10-06 — — EP disclosed
US-10741768-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2020-08-11 — — US disclosed
EP-3654395-A1 ORGANIC LIGHT EMITTING DIODE HAVING HIGH EFFICIENCY SFC Co., Ltd. (KR) 2020-05-20 — — EP disclosed
US-20170342318-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2017-11-30 — — US disclosed
US-20170342318-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2017-11-30 — — US disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 — — US disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 — — US disclosed
EP-3176158-A2 CONDENSED FLUORENE DERIVATIVE COMPRISING HETERO RING SFC Co., Ltd. (KR) 2017-06-07 — — EP disclosed
US-20170141322-A1 NOVEL AMINE COMPOUNDS FOR ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-05-18 — — US disclosed
US-20170141322-A1 NOVEL AMINE COMPOUNDS FOR ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-05-18 — — US disclosed
EP-3144302-A1 HETEROCYCLIC COMPOUND CONTAINING AROMATIC AMINE GROUP, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC Co., Ltd. (KR) 2017-03-22 — — EP disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 — — US disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING CCNE2, INF2, AFF4 ALOX5 862/4885PRNP 3749/4885HDAC8 1140/4885
US-20170141322-A1 NOVEL AMINE COMPOUNDS FOR ORGANIC LIGHT-EMITTING DIODE AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME DRD1, DRD4, DRD2 ALOX5 1093/4885PRNP 3537/4885HDAC8 3915/4885
US-11563181-B2 Amine compounds for organic light-emitting diode and organic light-emitting diode including the same DRD1, DRD4, DRD2 ALOX5 972/4885PRNP 3332/4885HDAC8 4177/4885
US-11532792-B2 Organic light emitting diode having high efficiency CYBA, SLC1A2, MAOB ALOX5 280/4885PRNP 4065/4885HDAC8 4860/4885
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring CCNE2, INF2, AFF4 ALOX5 862/4885PRNP 3749/4885HDAC8 1140/4885
US-10741768-B2 Organic light-emitting diode with high efficiency ALDH1A2, CYBA, LPO ALOX5 231/4885PRNP 2668/4885HDAC8 3775/4885
US-20170342318-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME CRY1, CRY2, ALDH1A2 ALOX5 326/4885PRNP 1889/4885HDAC8 2135/4885
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME DDC, TYR, AOC2 ALOX5 763/4885PRNP 3077/4885HDAC8 1514/4885
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same DDC, TYR, AOC2 ALOX5 763/4885PRNP 3077/4885HDAC8 1514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback