SCHEMBL187277

SCHEMBL187277

O=S(=O)(Nc1ccccc1)C(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.52
CA2 P00918 3/20 0.52
CA1 P00915 2/20 0.52
IL1RN P18510 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50
KMT2A Q03164 6/20 0.47
MEN1 O00255 4/20 0.47
PKM P14618 3/20 0.47
ALDH1A1 P00352 1/20 0.47
CA12 O43570 3/20 0.42
CA9 Q16790 3/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PGR P06401 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
NAT1 P18440 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diflumidone SCHEMBL43413 0.78 CA1 (0.66) CA2CA1ALDH1A1MAPTSMN1; SMN2
SCHEMBL4099446 0.77 KEAP1 (0.58) KEAP1CA2CA1IL1RNERAP1
SCHEMBL23562731 0.77 KMT2A (0.55) KMT2AMEN1ALDH1A1HTTSMN1; SMN2
SCHEMBL18722578 0.74 KEAP1 (0.54) KEAP1CA2CA1IL1RNERAP1
SCHEMBL18638754 0.74 KEAP1 (0.54) KEAP1CA2CA1IL1RNERAP1
SCHEMBL19655561 0.74 CA1 (0.41) CA2CA1KMT2AMEN1ALDH1A1
SCHEMBL22787430 0.74 HPGD (0.56) CA2KMT2AMEN1PKMALDH1A1
SCHEMBL17501458 0.74 CA2 (0.42) CA2CA1ALDH1A1CA12CA9
SCHEMBL971159 0.73 KEAP1 (0.58) KEAP1CA2CA1IL1RNERAP1
SCHEMBL21986558 0.73 HTR6 (0.41) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150021800-A1 HERBICIDAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO (JP) 2015-01-22 US claimed
US-8883687-B2 Herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-11-11 US claimed
US-8198217-B2 Composition for weeding KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-06-12 US claimed
US-20120100992-A1 HERBICIDAL COMPOSITION IKEUCHI TOSHIHIRO (JP) 2012-04-26 US claimed
CN-101001523-B Pesticide composition KUMIAI CHEMICAL INDUSTRY CO 2012-03-28 CN claimed
EP-1498030-B1 GRANULAR AGRICULTURAL-CHEMICAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO (JP) 2012-02-22 EP claimed
US-8114815-B2 Herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-14 US claimed
US-8067337-B2 Agricultural chemical composition KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2011-11-29 US claimed
US-7829499-B2 Granular pesticide preparation KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-09 US claimed
EP-2112881-B1 HERBICIDAL COMPOSITIONS COMPRISING DIFLUOROMETHANESULFONYLANILIDE AND ONE OR MORE HERBICIDES BAYER CROPSCIENCE AG (DE) 2010-09-22 EP claimed
US-7638506-B2 cationic surfactants; wear resistance; kneading, extrusion; sustained release KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-12-29 US claimed
US-20090105078-A1 Agricultural chemical composition KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) 2009-04-23 US claimed
US-20090082206-A1 Herbicidal Composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-03-26 US claimed
US-20080200337-A1 Mixed herbicide compositions for paddy field BAYER CROPSCIENCE (DE) 2008-08-21 US claimed
CN-101001523-A Pesticide composition KUMIAI CHEMICAL INDUSTRY CO (JP) 2007-07-18 CN claimed
US-20070105720-A1 Granular agrochemical composition OZAKI EISUKE 2007-05-10 US claimed
EP-1776863-A1 AGRICULTURAL CHEMICAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-04-25 EP claimed
US-20060287199-A1 Time-release agent comprising an aqueous solution of both nondisintegrating acid pesticide granules and a water soluble pesticide; a cationic surfactant and base; sulfonylureas and difluoromethanesulfonylanilide dissolve after 30 minutes; environmentally friendly; nonphytotoxic; simplification KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2006-12-21 US claimed
US-20050250648-A1 Granular agricultura-chemical composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-10 US claimed
EP-1498030-A1 GRANULAR AGRICULTURAL-CHEMICAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-01-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250648-A1 Granular agricultura-chemical composition PRKG1, PRKAG2, AGK KEAP1 2402/4885CA2 696/4885CA1 1996/4885
US-20090105078-A1 Agricultural chemical composition PDXK, DDT, SYMPK KEAP1 133/4885CA2 410/4885CA1 1028/4885
US-20120100992-A1 HERBICIDAL COMPOSITION DDT, CAT, DDC KEAP1 85/4885CA2 6/4885CA1 445/4885
US-20150021800-A1 HERBICIDAL COMPOSITION DDT, CAT, DDC KEAP1 85/4885CA2 6/4885CA1 445/4885
US-20060287199-A1 Time-release agent comprising an aqueous solution of both nondisintegrating acid pesticide granules and a water soluble pesticide; a cationic surfactant and base; sulfonylureas and difluoromethanesulfonylanilide dissolve after 30 minutes; environmentally friendly; nonphytotoxic; simplification GCG, CASP12, CTRL KEAP1 4128/4885CA2 26/4885CA1 145/4885
US-20080200337-A1 Mixed herbicide compositions for paddy field DDT, PFAS, AGPS KEAP1 1534/4885CA2 1132/4885CA1 1120/4885
US-20090082206-A1 Herbicidal Composition DDT, CAT, DDC KEAP1 85/4885CA2 6/4885CA1 445/4885
US-20070105720-A1 Granular agrochemical composition AGL, PLA2G2C, GYPA KEAP1 3704/4885CA2 773/4885CA1 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.