SCHEMBL18784138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Lithium Ion SCHEMBL18784153	0.97	COMT (0.48)	COMTTSHRHTTKDM4EMAPT
	Potassium Ion SCHEMBL18784160	0.97	COMT (0.48)	COMTTSHRHTTKDM4EMAPT
	SCHEMBL18784122	0.89	TSHR (0.42)	COMTTSHRHTTKDM4EMAPT
	SCHEMBL18784204	0.87	TSHR (0.40)	COMTTSHRHTTKDM4EMAPT
	Potassium Ion SCHEMBL18784182	0.86	TSHR (0.42)	COMTTSHRHTTKDM4EMAPT
	Lithium Ion SCHEMBL18784188	0.86	TSHR (0.42)	COMTTSHRHTTKDM4EMAPT
	Potassium Ion SCHEMBL18784201	0.84	TSHR (0.40)	COMTTSHRHTTKDM4EMAPT
	Lithium Ion SCHEMBL18784179	0.84	TSHR (0.40)	COMTTSHRHTTKDM4EMAPT
	SCHEMBL18784146	0.83	PABPC1 (0.40)	TSHRKDM4EMAPTNPSR1GAA
	SCHEMBL16834249	0.83	COMT (0.50)	COMTTSHRHTTKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.