SCHEMBL18784342

SCHEMBL18784342

CCCCC/C=C\C/C=C\CCCCCCCCOCCC1(CCOCCCCCCCC/C=C\C/C=C\CCCCC)CN(C)C1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
FAAH O00519 2/20 0.40
MGLL Q99685 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18784345 1.00 ALDH1A1 (0.41) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18800961 1.00 ALDH1A1 (0.41) ALDH1A1CNR1CNR2FAAHMGLL
Hydrochloric Acid SCHEMBL30654868 0.99 ALDH1A1 (0.40) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18784331 0.96 ALDH1A1 (0.42) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18784328 0.96 ALDH1A1 (0.42) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18800895 0.92 ALDH1A1 (0.40) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL22423618 0.89 ALDH1A1 (0.36) ALDH1A1
SCHEMBL18800951 0.88 ALDH1A1 (0.40) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18784349 0.88 ALDH1A1 (0.40) ALDH1A1CNR1CNR2FAAHMGLL
SCHEMBL18784351 0.88 ALDH1A1 (0.40) ALDH1A1CNR1CNR2FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545636-B2 Acyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2026-02-10 US disclosed
EP-4655402-A1 NUCLEIC ACID VACCINES FOR VARICELLA-ZOSTER VIRUS (VZV) Providence Therapeutics Holdings Inc. (CA) 2025-12-03 EP disclosed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 US disclosed
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-10-09 US disclosed
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MAN INC (US) 2025-05-15 US disclosed
US-20250073164-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2025-03-06 US disclosed
US-12215068-B2 Constrained lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2025-02-04 US disclosed
EP-4452928-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-10-30 EP disclosed
EP-4452934-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM Providence Therapeutics Holdings Inc. (CA) 2024-10-30 EP disclosed
WO-2024156053-A1 NUCLEIC ACID VACCINES FOR VARICELLA-ZOSTER VIRUS (VZV) PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2024-08-02 WO disclosed
WO-2023044343-A1 ACYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-03-23 WO disclosed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO disclosed
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE KYOWA KIRIN CO., LTD. (JP) 2020-11-26 US disclosed
EP-3162794-B1 ALKYL SUBSTITUTED AZETIDINES AS CATIONIC LIPID KYOWA KIRIN CO LTD (JP) 2020-09-16 EP disclosed
EP-3662913-A1 NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES Kyowa Kirin Co., Ltd. (JP) 2020-06-10 EP disclosed
EP-3662913-A1 NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES Kyowa Kirin Co., Ltd. (JP) 2020-06-10 EP disclosed
US-20170224619-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170224619-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170224619-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2017-08-10 US disclosed
EP-3162794-A1 CATIONIC LIPID Kyowa Hakko Kirin Co., Ltd. (JP) 2017-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313525-A1 CONSTRAINED LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP ALDH1A1 4876/4885CNR1 3077/4885CNR2 2889/4885
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR ALDH1A1 3260/4885CNR1 3876/4885CNR2 3684/4885
US-20250073164-A1 IONIZABLE DISULFIDE LIPIDS AND LIPID NANOPARTICLES DERIVED THEREFROM SGMS1, SGMS2, ABCB4 ALDH1A1 3146/4885CNR1 4587/4885CNR2 4337/4885
US-12545636-B2 Acyclic lipids and methods of use thereof PLTP, LNPEP, PCTP ALDH1A1 4885/4885CNR1 3071/4885CNR2 2980/4885
US-20170224619-A1 CATIONIC LIPID NPC1L1, NPC1, SGMS1 ALDH1A1 3134/4885CNR1 719/4885CNR2 1192/4885
US-12215068-B2 Constrained lipids and methods of use thereof SGMS1, SGMS2, LNPEP ALDH1A1 4876/4885CNR1 3077/4885CNR2 2889/4885
US-20250154102-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP ALDH1A1 4882/4885CNR1 3959/4885CNR2 3947/4885
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE LIPA, LIPC, PNLIP ALDH1A1 354/4885CNR1 3755/4885CNR2 3991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.