SCHEMBL18918451

SCHEMBL18918451

C=C(C)O[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.42
CA4 P22748 1/20 0.36
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34
LTA4H P09960 3/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ELANE P08246 1/20 0.33
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
LMNA P02545 1/20 0.31
NR1H2 P55055 1/20 0.31
BAX Q07812 1/20 0.31
MAOB P27338 2/20 0.31
ALDH1A1 P00352 2/20 0.30
RECQL P46063 1/20 0.30
SRC P12931 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3294457 0.96 PAX8 (0.42) PAX8CA4MTNR1AMTNR1BLTA4H
SCHEMBL2584263 0.82 ELANE (0.47) PAX8MTNR1AMTNR1BL3MBTL1ELANE
SCHEMBL25263655 0.78 MTNR1A (0.44) CA4MTNR1AMTNR1BTSHRL3MBTL1
SCHEMBL27648804 0.77 ALOX15 (0.43) CA4MTNR1AMTNR1BTSHRL3MBTL1
SCHEMBL6116693 0.75 GPR174 (0.40) PAX8CA4MTNR1AMTNR1BL3MBTL1
SCHEMBL301726 0.74 LTA4H (0.50) CA4LTA4HTSHRL3MBTL1CA5A
SCHEMBL15653550 0.71 LTA4H (0.47) CA4LTA4HTSHRL3MBTL1CA5A
SCHEMBL2582629 0.71 THRB (0.49) MTNR1AMTNR1BALDH1A1MAPT
SCHEMBL582104 0.70 ELANE (0.46) PAX8CA4LTA4HTSHRL3MBTL1
SCHEMBL1608970 0.70 CA4 (0.50) CA4LTA4HTSHRL3MBTL1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178876-B1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSION AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD SHINETSU CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-10227453-B2 Silicone rubber composition and cured product thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-03-12 US disclosed
EP-3178885-A1 SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF Shin-Etsu Chemical Co., Ltd. (JP) 2017-06-14 EP disclosed
EP-3178876-A1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSON AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2017-06-14 EP disclosed
US-20170158821-A1 SILICONE RUBBER COMPOSITION AND CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-08 US disclosed
US-20170158859-A1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSION AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-08 US disclosed