Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.36 |
| ▸ | FEN1 | P39748 | 8/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219732 | 0.94 | HSD11B1 (0.41) | APPHSD11B1AKR1C3AKR1C2KIF11 | |
| SCHEMBL18979181 | 0.72 | HSD11B1 (0.50) | APPHSD11B1ALOX5APFEN1MPL | |
| SCHEMBL19219733 | 0.68 | MAPT (0.51) | APPHSD11B1ALOX5APFEN1 | |
| SCHEMBL4056345 | 0.67 | APP (0.49) | APPHSD11B1AKR1C3AKR1C2KIF11 | |
| SCHEMBL17506513 | 0.66 | PTGS2 (0.40) | KIF11PTGS2 | |
| SCHEMBL13680603 | 0.64 | PTGS2 (0.50) | KIF11PTGS2 | |
| SCHEMBL13743069 | 0.63 | KIF11 (0.65) | APPKIF11ALOX5APFEN1PTGS2 | |
| SCHEMBL27586620 | 0.62 | APP (0.54) | APPAKR1C3AKR1C2KIF11ALOX5AP | |
| SCHEMBL9319095 | 0.62 | APP (0.58) | APPAKR1C3AKR1C2KIF11ALOX5AP | |
| SCHEMBL12570856 | 0.62 | AKR1C3 (0.69) | APPAKR1C3AKR1C2KIF11ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000112-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| EP-3766871-A1 | DIARYLIMIDAZOLE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2021-01-20 | — | — | EP | disclosed |
| EP-3181552-B1 | DIARYL IMIDAZOLE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-20200187501-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2020-06-18 | — | — | US | disclosed |
| US-20180289006-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2018-10-11 | — | — | US | disclosed |
| US-10021880-B2 | Diarylimidazole compound and harmful organism control agent | NIPPON SODA CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| EP-3181552-A1 | DIARYL IMIDAZOLE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2017-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10021880-B2 | Diarylimidazole compound and harmful organism control agent | NOX1, L3MBTL1, MRM1 | APP 4857/4885HSD11B1 769/4885AKR1C3 143/4885 |
| US-20200187501-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NOX1, L3MBTL1, MRM1 | APP 4857/4885HSD11B1 769/4885AKR1C3 143/4885 |
| US-20180289006-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NOX1, L3MBTL1, MRM1 | APP 4857/4885HSD11B1 769/4885AKR1C3 143/4885 |
| US-20220000112-A1 | DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT | NOX1, L3MBTL1, MRM1 | APP 4857/4885HSD11B1 769/4885AKR1C3 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.