Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511941 | 0.95 | KIF11 (0.48) | KIF11SLC2A1MAPTKMT2ATDP1 | |
| SCHEMBL26924248 | 0.95 | KIF11 (0.48) | KIF11SLC2A1MAPTKMT2ATDP1 | |
| SCHEMBL22392867 | 0.87 | SLC2A1 (0.51) | SLC2A1MAPTHTTIMPDH2ABCG2 | |
| SCHEMBL29768834 | 0.87 | SLC2A1 (0.51) | SLC2A1MAPTHTTIMPDH2ABCG2 | |
| SCHEMBL30925687 | 0.85 | MAT2A (0.56) | KIF11SLC2A1KMT2AMAT2AKDM4E | |
| SCHEMBL30925685 | 0.85 | MAT2A (0.56) | KIF11SLC2A1KMT2AMAT2AKDM4E | |
| SCHEMBL25658498 | 0.84 | SLC2A1 (0.44) | KIF11SLC2A1MAT2AKDM4EPTGS2 | |
| SCHEMBL8533470 | 0.84 | MAT2A (0.54) | KIF11MAPTKMT2ATDP1MAT2A | |
| SCHEMBL29505903 | 0.84 | MAT2A (0.54) | KIF11MAPTKMT2ATDP1MAT2A | |
| SCHEMBL19047285 | 0.84 | KDM4C (0.45) | SLC2A1MAT2AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414385-B2 | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases | THE UNIVERSITY OF CHICAGO | 2022-08-16 | — | — | US | claimed |
| US-10799494-B2 | Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2020-10-13 | — | — | US | claimed |
| US-20190151305-A1 | COMBINATION PRODUCT | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2019-05-23 | — | — | US | claimed |
| CN-110545815-B | Medical application of cytochrome bc1 complex inhibitor | 北京蔚蓝之源医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20240182421-A1 | SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-06-06 | — | — | US | disclosed |
| US-11964944-B2 | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases | THE UNIVERSITY OF CHICAGO (US) | 2024-04-23 | — | — | US | disclosed |
| EP-4308109-A1 | SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES | Oregon Health & Science University (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117042768-A | Synthesis of enodoxine-like quinolones | 俄勒冈健康与科学大学 | 2023-11-10 | — | — | CN | disclosed |
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-06-15 | — | — | US | disclosed |
| US-11414385-B2 | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases | THE UNIVERSITY OF CHICAGO | 2022-08-16 | — | — | US | disclosed |
| US-10799494-B2 | Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2020-10-13 | — | — | US | disclosed |
| US-10799494-B2 | Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2020-10-13 | — | — | US | disclosed |
| US-20200283391-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | THE UNIVERSITY OF CHICAGO | 2020-09-10 | — | — | US | disclosed |
| US-20200283391-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | THE UNIVERSITY OF CHICAGO | 2020-09-10 | — | — | US | disclosed |
| US-20190151305-A1 | COMBINATION PRODUCT | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2019-05-23 | — | — | US | disclosed |
| US-20190151305-A1 | COMBINATION PRODUCT | LIVERPOOL SCHOOL TROPICAL MEDICINE (GB) | 2019-05-23 | — | — | US | disclosed |
| WO-2017112678-A1 | COMPOUNDS AND METHODS FOR TREATING, DETECTING, AND IDENTIFYING COMPOUNDS TO TREAT APICOMPLEXAN PARASITIC DISEASES | MCLEOD RIMA (US) | 2017-06-29 | — | — | WO | disclosed |
| WO-2017103615-A1 | COMBINATION PRODUCT | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283391-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | TUBB1, MYADM, TUBB | KIF11 3261/4885SLC2A1 4082/4885MAPT 2969/4885 |
| US-10799494-B2 | Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor | NDUFB7, NDUFB3, NDUFB5 | KIF11 2588/4885SLC2A1 315/4885MAPT 1315/4885 |
| US-20240182421-A1 | SYNTHESIS OF ENDOCHIN-LIKE QUINOLONES | ENGASE, ESYT2, VPS4B | KIF11 3259/4885SLC2A1 4039/4885MAPT 4104/4885 |
| US-11964944-B2 | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases | TUBB1, MYADM, TUBB | KIF11 3312/4885SLC2A1 4114/4885MAPT 2933/4885 |
| US-11414385-B2 | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases | TUBB1, MYADM, TUBB | KIF11 3261/4885SLC2A1 4082/4885MAPT 2969/4885 |
| US-20230181564-A1 | Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites | CYP11B2, CYP11B1, COX5B | KIF11 3110/4885SLC2A1 4289/4885MAPT 2636/4885 |
| US-20190151305-A1 | COMBINATION PRODUCT | NDUFB5, NDUFB7, NDUFB10 | KIF11 1969/4885SLC2A1 374/4885MAPT 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.